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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SC5AB_HUMAN (Q8WWX8)

Summary

This is the summary of UniProt entry SC5AB_HUMAN (Q8WWX8).

Description: Sodium/myo-inositol cotransporter 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 675 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 7
disorder n/a 9 12
disorder n/a 14 17
transmembrane n/a 29 45
low_complexity n/a 29 41
Pfam SSF 58 487
transmembrane n/a 66 85
transmembrane n/a 105 125
transmembrane n/a 137 158
transmembrane n/a 178 202
transmembrane n/a 209 229
transmembrane n/a 269 287
transmembrane n/a 308 329
low_complexity n/a 375 388
transmembrane n/a 376 396
transmembrane n/a 417 436
low_complexity n/a 418 438
transmembrane n/a 448 472
transmembrane n/a 479 501
low_complexity n/a 482 496
transmembrane n/a 521 542
low_complexity n/a 526 539
transmembrane n/a 655 674

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8WWX8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MESGTSSPQP PQLDPLDAFP QKGLEPGDIA VLVLYFLFVL AVGLWSTVKT
50
51
KRDTVKGYFL AGGDMVWWPV GASLFASNVG SGHFIGLAGS GAATGISVSA
100
101
YELNGLFSVL MLAWIFLPIY IAGQVTTMPE YLRKRFGGIR IPIILAVLYL
150
151
FIYIFTKISV DMYAGAIFIQ QSLHLDLYLA IVGLLAITAV YTVAGGLAAV
200
201
IYTDALQTLI MLIGALTLMG YSFAAVGGME GLKEKYFLAL ASNRSENSSC
250
251
GLPREDAFHI FRDPLTSDLP WPGVLFGMSI PSLWYWCTDQ VIVQRTLAAK
300
301
NLSHAKGGAL MAAYLKVLPL FIMVFPGMVS RILFPDQVAC ADPEICQKIC
350
351
SNPSGCSDIA YPKLVLELLP TGLRGLMMAV MVAALMSSLT SIFNSASTIF
400
401
TMDLWNHLRP RASEKELMIV GRVFVLLLVL VSILWIPVVQ ASQGGQLFIY
450
451
IQSISSYLQP PVAVVFIMGC FWKRTNEKGA FWGLISGLLL GLVRLVLDFI
500
501
YVQPRCDQPD ERPVLVKSIH YLYFSMILST VTLITVSTVS WFTEPPSKEM
550
551
VSHLTWFTRH DPVVQKEQAP PAAPLSLTLS QNGMPEASSS SSVQFEMVQE
600
601
NTSKTHSCDM TPKQSKVVKA ILWLCGIQEK GKEELPARAE AIIVSLEENP
650
651
LVKTLLDVNL IFCVSCAIFI WGYFA                           
675
 

Show the unformatted sequence.

Checksums:
CRC64:44F7BA6D2FE92335
MD5:5ca6545b0c12b7383aee6c610848e61b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.