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7  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NDUS1_MOUSE (Q91VD9)

Summary

This is the summary of UniProt entry NDUS1_MOUSE (Q91VD9).

Description: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 727 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Fer2_4 29 107
Pfam NADH-G_4Fe-4S_3 113 152
Pfam Molybdopterin 301 629
disorder n/a 601 603
disorder n/a 607 610
Pfam NADH_dhqG_C 658 710

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q91VD9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLRIPIKRAL IGLSNSPKGY VRTTGTAASN LIEVFVDGQS VMVEPGTTVL
50
51
QACEKVGMQI PRFCYHERLS VAGNCRMCLV EIEKAPKVVA ACAMPVMKGW
100
101
NILTNSEKSK KAREGVMEFL LANHPLDCPI CDQGGECDLQ DQSMMFGSDR
150
151
SRFLEGKRAV EDKNIGPLVK TIMTRCIQCT RCIRFASEIA GVDDLGTTGR
200
201
GNDMQVGTYI EKMFMSELSG NVIDICPVGA LTSKPYAFTA RPWETRKTES
250
251
IDVMDAVGSN IVVSTRTGEV MRILPRMHED INEEWISDKT RFAYDGLKRQ
300
301
RLTEPMVRNE KGLLTYTSWE DALSRVAGML QNFEGNAVAA IAGGLVDAEA
350
351
LVALKDLLNK VDSDNLCTEE IFPTEGAGTD LRSNYLLNTT IAGVEEADVV
400
401
LLVGTNPRFE APLFNARIRK SWLHNDLKVA LIGSPVDLTY RYDHLGDSPK
450
451
ILQDIASGRH SFCEVLKDAK KPMVVLGSSA LQRDDGAAIL VAVSNMVQKI
500
501
RVTTGVAAEW KVMNILHRIA SQVAALDLGY KPGVEAIRKN PPKMLFLLGA
550
551
DGGCITRQDL PKDCFIVYQG HHGDVGAPMA DVILPGAAYT EKSATYVNTE
600
601
GRAQQTKVAV TPPGLAREDW KIIRALSEIA GITLPYDTLD QVRNRLEEVS
650
651
PNLVRYDDIE ETNYFQQASE LAKLVNQEVL ADPLVPPQLT IKDFYMTDSI
700
701
SRASQTMAKC VKAVTEGAQA VEEPSIC                         
727
 

Show the unformatted sequence.

Checksums:
CRC64:4A4B4BD6C330BB4F
MD5:4ee5a78d3fd279001075a3c007910ba4

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Fer2_4 29 - 107 6G2J G 6 - 84 Show 3D Structure View in InterPro
6G72 G 6 - 84 Show 3D Structure View in InterPro
6ZR2 G 6 - 84 Show 3D Structure View in InterPro
6ZTQ G 6 - 84 Show 3D Structure View in InterPro
7AK5 G 6 - 84 Show 3D Structure View in InterPro
7B93 G 6 - 84 Show 3D Structure View in InterPro
30 - 107 7AK6 G 7 - 84 Show 3D Structure View in InterPro
Molybdopterin 301 - 629 6G2J G 278 - 606 Show 3D Structure View in InterPro
6G72 G 278 - 606 Show 3D Structure View in InterPro
6ZR2 G 278 - 606 Show 3D Structure View in InterPro
6ZTQ G 278 - 606 Show 3D Structure View in InterPro
7AK5 G 278 - 606 Show 3D Structure View in InterPro
7AK6 G 278 - 606 Show 3D Structure View in InterPro
7B93 G 278 - 606 Show 3D Structure View in InterPro
NADH-G_4Fe-4S_3 113 - 152 6G2J G 90 - 129 Show 3D Structure View in InterPro
6G72 G 90 - 129 Show 3D Structure View in InterPro
6ZR2 G 90 - 129 Show 3D Structure View in InterPro
6ZTQ G 90 - 129 Show 3D Structure View in InterPro
7AK5 G 90 - 129 Show 3D Structure View in InterPro
7AK6 G 90 - 129 Show 3D Structure View in InterPro
7B93 G 90 - 129 Show 3D Structure View in InterPro
NADH_dhqG_C 658 - 710 6G2J G 635 - 687 Show 3D Structure View in InterPro
6G72 G 635 - 687 Show 3D Structure View in InterPro
6ZR2 G 635 - 687 Show 3D Structure View in InterPro
6ZTQ G 635 - 687 Show 3D Structure View in InterPro
7AK5 G 635 - 687 Show 3D Structure View in InterPro
7AK6 G 635 - 687 Show 3D Structure View in InterPro
7B93 G 635 - 687 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;