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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: TADBP_MOUSE (Q921F2)

Summary

This is the summary of UniProt entry TADBP_MOUSE (Q921F2).

Description: TAR DNA-binding protein 43
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 414 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 2 6
disorder n/a 8 22
disorder n/a 84 94
Pfam RRM_1 106 172
Pfam RRM_1 193 243
disorder n/a 260 304
low_complexity n/a 272 315
low_complexity n/a 320 328
disorder n/a 335 375
low_complexity n/a 341 357
low_complexity n/a 367 379
disorder n/a 378 389
low_complexity n/a 385 403
disorder n/a 395 404
disorder n/a 408 409
disorder n/a 412 414

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q921F2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC
50
51
MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV
100
101
QKTSDLIVLG LPWKTTEQDL KDYFSTFGEV LMVQVKKDLK TGHSKGFGFV
150
151
RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSPDEPLRS RKVFVGRCTE
200
201
DMTAEELQQF FCQYGEVVDV FIPKPFRAFA FVTFADDKVA QSLCGEDLII
250
251
KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG
300
301
NNQGGNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS
350
351
GNNQSQGSMQ REPNQAFGSG NNSYSGSNSG APLGWGSASN AGSGSGFNGG
400
401
FGSSMDSKSS GWGM                                       
414
 

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Checksums:
CRC64:2BE6A695EC2CA106
MD5:7f13797d113dd791c6aa9006ea9b7bfa

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RRM_1 193 - 243 3D2W A 193 - 243 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.