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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PRCC_HUMAN (Q92733)

Summary

This is the summary of UniProt entry PRCC_HUMAN (Q92733).

Description: Proline-rich protein PRCC
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 491 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 325
low_complexity n/a 7 26
low_complexity n/a 40 71
low_complexity n/a 68 95
low_complexity n/a 103 138
low_complexity n/a 230 258
Pfam PRCC 275 491
low_complexity n/a 284 296
low_complexity n/a 296 310
disorder n/a 327 332
disorder n/a 334 348
low_complexity n/a 355 369
disorder n/a 370 371
disorder n/a 374 377
disorder n/a 379 385
disorder n/a 387 401
disorder n/a 405 413
disorder n/a 422 427
disorder n/a 436 459
disorder n/a 471 477
disorder n/a 482 483
disorder n/a 486 488

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q92733. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSLVAYASSD ESEPDEAEPE PEEEEAVAPT SGPALGGLFA SLPAPKGPAL
50
51
LPPPPQMLAP AFPPPLLLPP PTGDPRLQPP PPLPFGLGGF PPPPGVSPAE
100
101
AAGVGEGLGL GLPSPRGPGL NLPPPIGGAG PPLGLPKPKK RKEPVKIAAP
150
151
ELHKGDSDSE EDEPTKKKTI LQGSSEGTGL SALLPQPKNL TVKETNRLLL
200
201
PHAFSRKPSD GSPDTKPSRL ASKTKTSSLA PVVGTTTTTP SPSAIKAAAK
250
251
SAALQVTKQI TQEEDDSDEE VAPENFFSLP EKAEPPGVEP YPYPIPTVPE
300
301
ELPPGTEPEP AFQDDAANAP LEFKMAAGSS GAPWMPKPGD DYSYNQFSTY
350
351
GDANAAGAYY QDYYSGGYYP AQDPALVPPQ EIAPDASFID DEAFKRLQGK
400
401
RNRGREEINF VEIKGDDQLS GAQQWMTKSL TEEKTMKSFS KKKGEQPTGQ
450
451
QRRKHQITYL IHQAKERELE LKNTWSENKL SRRQTQAKYG F         
491
 

Show the unformatted sequence.

Checksums:
CRC64:F99CFD9D42725D57
MD5:2102452a5015a00c5d46a0af80883d3a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;