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9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KAT2A_HUMAN (Q92830)

Summary

This is the summary of UniProt entry KAT2A_HUMAN (Q92830).

Description: Histone acetyltransferase KAT2A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 837 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 100
low_complexity n/a 3 79
low_complexity n/a 81 92
Pfam PCAF_N 86 336
disorder n/a 121 138
disorder n/a 381 383
disorder n/a 385 388
low_complexity n/a 389 402
disorder n/a 390 394
low_complexity n/a 407 424
disorder n/a 411 414
disorder n/a 417 442
disorder n/a 477 479
disorder n/a 483 486
Pfam Acetyltransf_1 517 627
low_complexity n/a 666 682
coiled_coil n/a 668 688
low_complexity n/a 716 730
Pfam Bromodomain 737 820

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q92830. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEPSQAPTP APAAQPRPLQ SPAPAPTPTP APSPASAPIP TPTPAPAPAP
50
51
AAAPAGSTGT GGPGVGSGGA GSGGDPARPG LSQQQRASQR KAQVRGLPRA
100
101
KKLEKLGVFS ACKANETCKC NGWKNPKPPT APRMDLQQPA ANLSELCRSC
150
151
EHPLADHVSH LENVSEDEIN RLLGMVVDVE NLFMSVHKEE DTDTKQVYFY
200
201
LFKLLRKCIL QMTRPVVEGS LGSPPFEKPN IEQGVLNFVQ YKFSHLAPRE
250
251
RQTMFELSKM FLLCLNYWKL ETPAQFRQRS QAEDVATYKV NYTRWLCYCH
300
301
VPQSCDSLPR YETTHVFGRS LLRSIFTVTR RQLLEKFRVE KDKLVPEKRT
350
351
LILTHFPKFL SMLEEEIYGA NSPIWESGFT MPPSEGTQLV PRPASVSAAV
400
401
VPSTPIFSPS MGGGSNSSLS LDSAGAEPMP GEKRTLPENL TLEDAKRLRV
450
451
MGDIPMELVN EVMLTITDPA AMLGPETSLL SANAARDETA RLEERRGIIE
500
501
FHVIGNSLTP KANRRVLLWL VGLQNVFSHQ LPRMPKEYIA RLVFDPKHKT
550
551
LALIKDGRVI GGICFRMFPT QGFTEIVFCA VTSNEQVKGY GTHLMNHLKE
600
601
YHIKHNILYF LTYADEYAIG YFKKQGFSKD IKVPKSRYLG YIKDYEGATL
650
651
MECELNPRIP YTELSHIIKK QKEIIKKLIE RKQAQIRKVY PGLSCFKEGV
700
701
RQIPVESVPG IRETGWKPLG KEKGKELKDP DQLYTTLKNL LAQIKSHPSA
750
751
WPFMEPVKKS EAPDYYEVIR FPIDLKTMTE RLRSRYYVTR KLFVADLQRV
800
801
IANCREYNPP DSEYCRCASA LEKFFYFKLK EGGLIDK              
837
 

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Checksums:
CRC64:728CC8ACF08600EA
MD5:bf8fff7a887883a69a35659b21c3da8a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Acetyltransf_1 517 - 627 1Z4R A 517 - 627 Jmol OpenAstexViewer
5H84 A 23 - 133 Jmol OpenAstexViewer
5H86 A 23 - 133 Jmol OpenAstexViewer
5TRL A 517 - 627 Jmol OpenAstexViewer
B 517 - 627 Jmol OpenAstexViewer
C 517 - 627 Jmol OpenAstexViewer
D 517 - 627 Jmol OpenAstexViewer
E 517 - 627 Jmol OpenAstexViewer
F 517 - 627 Jmol OpenAstexViewer
G 517 - 627 Jmol OpenAstexViewer
H 517 - 627 Jmol OpenAstexViewer
5TRM A 517 - 627 Jmol OpenAstexViewer
B 517 - 627 Jmol OpenAstexViewer
C 517 - 627 Jmol OpenAstexViewer
D 517 - 627 Jmol OpenAstexViewer
E 517 - 627 Jmol OpenAstexViewer
F 517 - 627 Jmol OpenAstexViewer
G 517 - 627 Jmol OpenAstexViewer
H 517 - 627 Jmol OpenAstexViewer
I 517 - 627 Jmol OpenAstexViewer
J 517 - 627 Jmol OpenAstexViewer
K 517 - 627 Jmol OpenAstexViewer
L 517 - 627 Jmol OpenAstexViewer
M 517 - 627 Jmol OpenAstexViewer
N 517 - 627 Jmol OpenAstexViewer
O 517 - 627 Jmol OpenAstexViewer
P 517 - 627 Jmol OpenAstexViewer
Q 517 - 627 Jmol OpenAstexViewer
R 517 - 627 Jmol OpenAstexViewer
S 517 - 627 Jmol OpenAstexViewer
T 517 - 627 Jmol OpenAstexViewer
U 517 - 627 Jmol OpenAstexViewer
V 517 - 627 Jmol OpenAstexViewer
W 517 - 627 Jmol OpenAstexViewer
X 517 - 627 Jmol OpenAstexViewer
Bromodomain 737 - 820 1F68 A 737 - 820 Jmol OpenAstexViewer
3D7C A 737 - 820 Jmol OpenAstexViewer
B 737 - 820 Jmol OpenAstexViewer
5MLJ A 737 - 820 Jmol OpenAstexViewer
B 737 - 820 Jmol OpenAstexViewer
6J3P A 737 - 820 Jmol OpenAstexViewer
B 737 - 820 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.