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9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RENT1_HUMAN (Q92900)

Summary

This is the summary of UniProt entry RENT1_HUMAN (Q92900).

Description: Regulator of nonsense transcripts 1 EC=3.6.4.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1129 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 4
disorder n/a 6 72
low_complexity n/a 46 71
disorder n/a 74 77
disorder n/a 79 83
disorder n/a 85 87
disorder n/a 100 101
low_complexity n/a 105 114
Pfam UPF1_Zn_bind 121 272
disorder n/a 279 282
Pfam DUF5599 324 425
Pfam AAA_11 481 605
Pfam AAA_11 582 684
disorder n/a 583 594
disorder n/a 602 605
Pfam AAA_12 691 888
disorder n/a 956 958
disorder n/a 963 975
disorder n/a 994 996
low_complexity n/a 999 1005
disorder n/a 1003 1101
low_complexity n/a 1017 1030
low_complexity n/a 1070 1085
disorder n/a 1104 1125

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q92900. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSVEAYGPSS QTLTFLDTEE AELLGADTQG SEFEFTDFTL PSQTQTPPGG
50
51
PGGPGGGGAG GPGGAGAGAA AGQLDAQVGP EGILQNGAVD DSVAKTSQLL
100
101
AELNFEEDEE DTYYTKDLPI HACSYCGIHD PACVVYCNTS KKWFCNGRGN
150
151
TSGSHIVNHL VRAKCKEVTL HKDGPLGETV LECYNCGCRN VFLLGFIPAK
200
201
ADSVVVLLCR QPCASQSSLK DINWDSSQWQ PLIQDRCFLS WLVKIPSEQE
250
251
QLRARQITAQ QINKLEELWK ENPSATLEDL EKPGVDEEPQ HVLLRYEDAY
300
301
QYQNIFGPLV KLEADYDKKL KESQTQDNIT VRWDLGLNKK RIAYFTLPKT
350
351
DSGNEDLVII WLRDMRLMQG DEICLRYKGD LAPLWKGIGH VIKVPDNYGD
400
401
EIAIELRSSV GAPVEVTHNF QVDFVWKSTS FDRMQSALKT FAVDETSVSG
450
451
YIYHKLLGHE VEDVIIKCQL PKRFTAQGLP DLNHSQVYAV KTVLQRPLSL
500
501
IQGPPGTGKT VTSATIVYHL ARQGNGPVLV CAPSNIAVDQ LTEKIHQTGL
550
551
KVVRLCAKSR EAIDSPVSFL ALHNQIRNMD SMPELQKLQQ LKDETGELSS
600
601
ADEKRYRALK RTAERELLMN ADVICCTCVG AGDPRLAKMQ FRSILIDEST
650
651
QATEPECMVP VVLGAKQLIL VGDHCQLGPV VMCKKAAKAG LSQSLFERLV
700
701
VLGIRPIRLQ VQYRMHPALS AFPSNIFYEG SLQNGVTAAD RVKKGFDFQW
750
751
PQPDKPMFFY VTQGQEEIAS SGTSYLNRTE AANVEKITTK LLKAGAKPDQ
800
801
IGIITPYEGQ RSYLVQYMQF SGSLHTKLYQ EVEIASVDAF QGREKDFIIL
850
851
SCVRANEHQG IGFLNDPRRL NVALTRARYG VIIVGNPKAL SKQPLWNHLL
900
901
NYYKEQKVLV EGPLNNLRES LMQFSKPRKL VNTINPGARF MTTAMYDARE
950
951
AIIPGSVYDR SSQGRPSSMY FQTHDQIGMI SAGPSHVAAM NIPIPFNLVM
1000
1001
PPMPPPGYFG QANGPAAGRG TPKGKTGRGG RQKNRFGLPG PSQTNLPNSQ
1050
1051
ASQDVASQPF SQGALTQGYI SMSQPSQMSQ PGLSQPELSQ DSYLGDEFKS
1100
1101
QIDVALSQDS TYQGERAYQH GGVTGLSQY                       
1129
 

Show the unformatted sequence.

Checksums:
CRC64:6CCA6FE42B15BA28
MD5:2367366a4f9f86d3d5be09dcf486a733

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
AAA_11 481 - 605 2GJK A 470 - 594 Jmol OpenAstexViewer
2GK6 A 470 - 594 Jmol OpenAstexViewer
B 470 - 594 Jmol OpenAstexViewer
2GK7 A 470 - 594 Jmol OpenAstexViewer
2WJV A 470 - 594 Jmol OpenAstexViewer
B 470 - 594 Jmol OpenAstexViewer
2WJY A 470 - 594 Jmol OpenAstexViewer
2XZO A 470 - 594 Jmol OpenAstexViewer
2XZP A 470 - 594 Jmol OpenAstexViewer
6EJ5 A 481 - 605 Jmol OpenAstexViewer
582 - 684 2GJK A 571 - 673 Jmol OpenAstexViewer
2GK6 A 571 - 673 Jmol OpenAstexViewer
B 571 - 673 Jmol OpenAstexViewer
2GK7 A 571 - 673 Jmol OpenAstexViewer
2WJV A 571 - 673 Jmol OpenAstexViewer
B 571 - 673 Jmol OpenAstexViewer
2WJY A 571 - 673 Jmol OpenAstexViewer
2XZO A 571 - 673 Jmol OpenAstexViewer
2XZP A 571 - 673 Jmol OpenAstexViewer
6EJ5 A 582 - 684 Jmol OpenAstexViewer
AAA_12 691 - 888 2GJK A 680 - 877 Jmol OpenAstexViewer
2GK6 A 680 - 877 Jmol OpenAstexViewer
B 680 - 877 Jmol OpenAstexViewer
2GK7 A 680 - 877 Jmol OpenAstexViewer
2WJV A 680 - 877 Jmol OpenAstexViewer
B 680 - 877 Jmol OpenAstexViewer
2WJY A 680 - 877 Jmol OpenAstexViewer
2XZO A 680 - 877 Jmol OpenAstexViewer
2XZP A 680 - 877 Jmol OpenAstexViewer
6EJ5 A 691 - 888 Jmol OpenAstexViewer
DUF5599 324 - 425 2GJK A 324 - 414 Jmol OpenAstexViewer
2GK6 A 324 - 414 Jmol OpenAstexViewer
B 324 - 414 Jmol OpenAstexViewer
2GK7 A 324 - 414 Jmol OpenAstexViewer
2WJV A 324 - 414 Jmol OpenAstexViewer
B 324 - 414 Jmol OpenAstexViewer
2WJY A 324 - 414 Jmol OpenAstexViewer
2XZO A 324 - 414 Jmol OpenAstexViewer
2XZP A 324 - 414 Jmol OpenAstexViewer
6EJ5 A 324 - 425 Jmol OpenAstexViewer
UPF1_Zn_bind 121 - 272 2IYK A 11 - 162 Jmol OpenAstexViewer
B 11 - 162 Jmol OpenAstexViewer
2WJV A 121 - 272 Jmol OpenAstexViewer
B 121 - 272 Jmol OpenAstexViewer
2WJY A 121 - 272 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.