Summary
This is the summary of UniProt entry KCNN1_HUMAN (Q92952).
Description: | Small conductance calcium-activated potassium channel protein 1 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 543 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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Source | Domain | Start | End |
---|---|---|---|
disorder | n/a | 1 | 94 |
low_complexity | n/a | 49 | 82 |
Pfam | SK_channel | 92 | 208 |
transmembrane | n/a | 106 | 125 |
transmembrane | n/a | 137 | 160 |
low_complexity | n/a | 236 | 247 |
Pfam | Ion_trans_2 | 275 | 370 |
transmembrane | n/a | 277 | 297 |
transmembrane | n/a | 317 | 334 |
transmembrane | n/a | 346 | 366 |
Pfam | CaMBD | 384 | 461 |
disorder | n/a | 424 | 425 |
disorder | n/a | 450 | 453 |
coiled_coil | n/a | 468 | 495 |
disorder | n/a | 479 | 480 |
disorder | n/a | 501 | 541 |
low_complexity | n/a | 502 | 523 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q92952. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MNSHSYNGSV GRPLGSGPGA LGRDPPDPEA GHPPQPPHSP GLQVVVAKSE
50 51
PARPSPGSPR GQPQDQDDDE DDEEDEAGRQ RASGKPSNVG HRLGHRRALF
100 101
EKRKRLSDYA LIFGMFGIVV MVTETELSWG VYTKESLYSF ALKCLISLST
150 151
AILLGLVVLY HAREIQLFMV DNGADDWRIA MTCERVFLIS LELAVCAIHP
200 201
VPGHYRFTWT ARLAFTYAPS VAEADVDVLL SIPMFLRLYL LGRVMLLHSK
250 251
IFTDASSRSI GALNKITFNT RFVMKTLMTI CPGTVLLVFS ISSWIIAAWT
300 301
VRVCERYHDK QEVTSNFLGA MWLISITFLS IGYGDMVPHT YCGKGVCLLT
350 351
GIMGAGCTAL VVAVVARKLE LTKAEKHVHN FMMDTQLTKR VKNAAANVLR
400 401
ETWLIYKHTR LVKKPDQARV RKHQRKFLQA IHQAQKLRSV KIEQGKLNDQ
450 451
ANTLTDLAKT QTVMYDLVSE LHAQHEELEA RLATLESRLD ALGASLQALP
500 501
GLIAQAIRPP PPPLPPRPGP GPQDQAARSS PCRWTPVAPS DCG
543
Show the unformatted sequence. |
Checksums: |
CRC64:13EFF47C263BCB11
MD5:1c6eb53089930d08f99aa55b2e2e509a
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
Very High (pLDDT > 90) | |
Confident (90 > pLDDT > 70) | |
Low (70 > pLDDT > 50) | |
Very Low (pLDDT < 50) |