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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DVL3_HUMAN (Q92997)

Summary

This is the summary of UniProt entry DVL3_HUMAN (Q92997).

Description: Segment polarity protein dishevelled homolog DVL-3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 716 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam DIX 2 80
disorder n/a 57 58
disorder n/a 85 234
Pfam Dishevelled 87 245
low_complexity n/a 174 187
low_complexity n/a 184 210
low_complexity n/a 211 230
low_complexity n/a 226 243
Pfam PDZ 249 334
disorder n/a 348 349
low_complexity n/a 377 395
disorder n/a 388 389
Pfam DEP 425 494
Pfam Dsh_C 500 706
disorder n/a 505 528
low_complexity n/a 530 553
disorder n/a 532 708
low_complexity n/a 556 566
low_complexity n/a 560 585
low_complexity n/a 588 605
low_complexity n/a 628 649
low_complexity n/a 652 683

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q92997. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGETKIIYHL DGQETPYLVK LPLPAERVTL ADFKGVLQRP SYKFFFKSMD
50
51
DDFGVVKEEI SDDNAKLPCF NGRVVSWLVS AEGSHPDPAP FCADNPSELP
100
101
PPMERTGGIG DSRPPSFHPH AGGGSQENLD NDTETDSLVS AQRERPRRRD
150
151
GPEHATRLNG TAKGERRREP GGYDSSSTLM SSELETTSFF DSDEDDSTSR
200
201
FSSSTEQSSA SRLMRRHKRR RRKQKVSRIE RSSSFSSITD STMSLNIITV
250
251
TLNMEKYNFL GISIVGQSNE RGDGGIYIGS IMKGGAVAAD GRIEPGDMLL
300
301
QVNEINFENM SNDDAVRVLR EIVHKPGPIT LTVAKCWDPS PRGCFTLPRS
350
351
EPIRPIDPAA WVSHTAAMTG TFPAYGMSPS LSTITSTSSS ITSSIPDTER
400
401
LDDFHLSIHS DMAAIVKAMA SPESGLEVRD RMWLKITIPN AFIGSDVVDW
450
451
LYHNVEGFTD RREARKYASN LLKAGFIRHT VNKITFSEQC YYIFGDLCGN
500
501
MANLSLHDHD GSSGASDQDT LAPLPHPGAA PWPMAFPYQY PPPPHPYNPH
550
551
PGFPELGYSY GGGSASSQHS EGSRSSGSNR SGSDRRKEKD PKAGDSKSGG
600
601
SGSESDHTTR SSLRGPRERA PSERSGPAAS EHSHRSHHSL ASSLRSHHTH
650
651
PSYGPPGVPP LYGPPMLMMP PPPAAMGPPG APPGRDLASV PPELTASRQS
700
701
FRMAMGNPSE FFVDVM                                     
716
 

Show the unformatted sequence.

Checksums:
CRC64:B1A55EBF9507D06E
MD5:1378bcacbe839ee4f5404ab6f8de6aac

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.