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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: WNT8B_HUMAN (Q93098)

Summary

This is the summary of UniProt entry WNT8B_HUMAN (Q93098).

Description: Protein Wnt-8b
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 351 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 22
Pfam wnt 34 334
low_complexity n/a 120 131
disorder n/a 158 164
disorder n/a 167 168
low_complexity n/a 273 285
disorder n/a 344 351

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q93098. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFLSKPSVYI CLFTCVLQLS HSWSVNNFLM TGPKAYLIYS SSVAAGAQSG
50
51
IEECKYQFAW DRWNCPERAL QLSSHGGLRS ANRETAFVHA ISSAGVMYTL
100
101
TRNCSLGDFD NCGCDDSRNG QLGGQGWLWG GCSDNVGFGE AISKQFVDAL
150
151
ETGQDARAAM NLHNNEAGRK AVKGTMKRTC KCHGVSGSCT TQTCWLQLPE
200
201
FREVGAHLKE KYHAALKVDL LQGAGNSAAG RGAIADTFRS ISTRELVHLE
250
251
DSPDYCLENK TLGLLGTEGR ECLRRGRALG RWERRSCRRL CGDCGLAVEE
300
301
RRAETVSSCN CKFHWCCAVR CEQCRRRVTK YFCSRAERPR GGAAHKPGRK
350
351
P                                                     
351
 

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Checksums:
CRC64:DD242070948813F8
MD5:fa1c6be68f2436dac293e83bdf13a246

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;