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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: VWCE_HUMAN (Q96DN2)

Summary

This is the summary of UniProt entry VWCE_HUMAN (Q96DN2).

Description: von Willebrand factor C and EGF domain-containing protein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 955 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 21
low_complexity n/a 2 15
Pfam EGF_CA 142 179
Pfam EGF_CA 220 261
disorder n/a 272 273
disorder n/a 280 329
low_complexity n/a 293 311
low_complexity n/a 313 330
disorder n/a 351 380
Pfam VWC 386 440
low_complexity n/a 483 498
Pfam VWC 501 559
Pfam VWC 629 684
Pfam VWC 687 742
low_complexity n/a 733 748
disorder n/a 753 768
disorder n/a 776 784
disorder n/a 794 796
low_complexity n/a 795 806
disorder n/a 806 883
low_complexity n/a 843 864
low_complexity n/a 857 871
disorder n/a 886 892
disorder n/a 894 955
low_complexity n/a 920 935

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96DN2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MWAGLLLRAA CVALLLPGAP ARGYTGRKPP GHFAAERRRL GPHVCLSGFG
50
51
SGCCPGWAPS MGGGHCTLPL CSFGCGSGIC IAPNVCSCQD GEQGATCPET
100
101
HGPCGEYGCD LTCNHGGCQE VARVCPVGFS MTETAVGIRC TDIDECVTSS
150
151
CEGHCVNTEG GFVCECGPGM QLSADRHSCQ DTDECLGTPC QQRCKNSIGS
200
201
YKCSCRTGFH LHGNRHSCVD VNECRRPLER RVCHHSCHNT VGSFLCTCRP
250
251
GFRLRADRVS CEAFPKAVLA PSAILQPRQH PSKMLLLLPE AGRPALSPGH
300
301
SPPSGAPGPP AGVRTTRLPS PTPRLPTSSP SAPVWLLSTL LATPVPTASL
350
351
LGNLRPPSLL QGEVMGTPSS PRGPESPRLA AGPSPCWHLG AMHESRSRWT
400
401
EPGCSQCWCE DGKVTCEKVR CEAACSHPIP SRDGGCCPSC TGCFHSGVVR
450
451
AEGDVFSPPN ENCTVCVCLA GNVSCISPEC PSGPCQTPPQ TDCCTCVPVR
500
501
CYFHGRWYAD GAVFSGGGDE CTTCVCQNGE VECSFMPCPE LACPREEWRL
550
551
GPGQCCFTCQ EPTPSTGCSL DDNGVEFPIG QIWSPGDPCE LCICQADGSV
600
601
SCKRTDCVDS CPHPIRIPGQ CCPDCSAGCT YTGRIFYNNE TFPSVLDPCL
650
651
SCICLLGSVA CSPVDCPITC TYPFHPDGEC CPVCRDCNYE GRKVANGQVF
700
701
TLDDEPCTRC TCQLGEVSCE KVPCQRACAD PALLPGDCCS SCPDSLSPLE
750
751
EKQGLSPHGN VAFSKAGRSL HGDTEAPVNC SSCPGPPTAS PSRPVLHLLQ
800
801
LLLRTNLMKT QTLPTSPAGA HGPHSLALGL TATFPGEPGA SPRLSPGPST
850
851
PPGAPTLPLA SPGAPQPPPV TPERSFSASG AQIVSRWPPL PGTLLTEASA
900
901
LSMMDPSPSK TPITLLGPRV LSPTTSRLST ALAATTHPGP QQPPVGASRG
950
951
EESTM                                                 
955
 

Show the unformatted sequence.

Checksums:
CRC64:B745618AD37E712B
MD5:7c928e57fbc170297152231749221906

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.