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14  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RNF31_HUMAN (Q96EP0)

Summary

This is the summary of UniProt entry RNF31_HUMAN (Q96EP0).

Description: E3 ubiquitin-protein ligase RNF31 EC=2.3.2.27
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1072 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam PUB_1 1 65
low_complexity n/a 33 46
Pfam PUB 69 150
disorder n/a 129 143
low_complexity n/a 147 163
disorder n/a 173 180
disorder n/a 198 208
low_complexity n/a 200 215
disorder n/a 254 259
disorder n/a 261 263
disorder n/a 265 280
low_complexity n/a 280 293
disorder n/a 282 290
low_complexity n/a 330 346
disorder n/a 336 337
disorder n/a 340 344
disorder n/a 443 491
low_complexity n/a 453 463
low_complexity n/a 458 471
Pfam HOIP-UBA 483 628
disorder n/a 545 546
disorder n/a 627 638
Pfam IBR 779 841
Pfam E3_UbLigase_RBR 940 1032
low_complexity n/a 956 967
disorder n/a 982 983
disorder n/a 1032 1041
disorder n/a 1044 1055
disorder n/a 1064 1072

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96EP0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPGEEEERAF LVAREELASA LRRDSGQAFS LEQLRPLLAS SLPLAARYLQ
50
51
LDAARLVRCN AHGEPRNYLN TLSTALNILE KYGRNLLSPQ RPRYWRGVKF
100
101
NNPVFRSTVD AVQGGRDVLR LYGYTEEQPD GLSFPEGQEE PDEHQVATVT
150
151
LEVLLLRTEL SLLLQNTHPR QQALEQLLED KVEDDMLQLS EFDPLLREIA
200
201
PGPLTTPSVP GSTPGPCFLC GSAPGTLHCP SCKQALCPAC DHLFHGHPSR
250
251
AHHLRQTLPG VLQGTHLSPS LPASAQPRPQ STSLLALGDS SLSSPNPASA
300
301
HLPWHCAACA MLNEPWAVLC VACDRPRGCK GLGLGTEGPQ GTGGLEPDLA
350
351
RGRWACQSCT FENEAAAVLC SICERPRLAQ PPSLVVDSRD AGICLQPLQQ
400
401
GDALLASAQS QVWYCIHCTF CNSSPGWVCV MCNRTSSPIP AQHAPRPYAS
450
451
SLEKGPPKPG PPRRLSAPLP SSCGDPEKQR QDKMREEGLQ LVSMIREGEA
500
501
AGACPEEIFS ALQYSGTEVP LQWLRSELPY VLEMVAELAG QQDPGLGAFS
550
551
CQEARRAWLD RHGNLDEAVE ECVRTRRRKV QELQSLGFGP EEGSLQALFQ
600
601
HGGDVSRALT ELQRQRLEPF RQRLWDSGPE PTPSWDGPDK QSLVRRLLAV
650
651
YALPSWGRAE LALSLLQETP RNYELGDVVE AVRHSQDRAF LRRLLAQECA
700
701
VCGWALPHNR MQALTSCECT ICPDCFRQHF TIALKEKHIT DMVCPACGRP
750
751
DLTDDTQLLS YFSTLDIQLR ESLEPDAYAL FHKKLTEGVL MRDPKFLWCA
800
801
QCSFGFIYER EQLEATCPQC HQTFCVRCKR QWEEQHRGRS CEDFQNWKRM
850
851
NDPEYQAQGL AMYLQENGID CPKCKFSYAL ARGGCMHFHC TQCRHQFCSG
900
901
CYNAFYAKNK CPEPNCRVKK SLHGHHPRDC LFYLRDWTAL RLQKLLQDNN
950
951
VMFNTEPPAG ARAVPGGGCR VIEQKEVPNG LRDEACGKET PAGYAGLCQA
1000
1001
HYKEYLVSLI NAHSLDPATL YEVEELETAT ERYLHVRPQP LAGEDPPAYQ
1050
1051
ARLLQKLTEE VPLGQSIPRR RK                              
1072
 

Show the unformatted sequence.

Checksums:
CRC64:CFAD183A14F764BA
MD5:375205e098174bec97bcee23df06a453

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
E3_UbLigase_RBR 940 - 1011 5EDV A 940 - 1011 Jmol OpenAstexViewer
940 - 1032 4LJO A 940 - 1032 Jmol OpenAstexViewer
4LJP A 940 - 1032 Jmol OpenAstexViewer
4LJQ A 940 - 1032 Jmol OpenAstexViewer
B 940 - 1032 Jmol OpenAstexViewer
C 940 - 1032 Jmol OpenAstexViewer
D 940 - 1032 Jmol OpenAstexViewer
5EDV B 940 - 1032 Jmol OpenAstexViewer
HOIP-UBA 483 - 613 5X0W C 483 - 613 Jmol OpenAstexViewer
483 - 615 5X0W A 483 - 615 Jmol OpenAstexViewer
483 - 622 5X0W G 483 - 622 Jmol OpenAstexViewer
483 - 626 5X0W E 483 - 626 Jmol OpenAstexViewer
483 - 627 4DBG B 483 - 627 Jmol OpenAstexViewer
IBR 779 - 841 2CT7 A 8 - 70 Jmol OpenAstexViewer
5EDV A 779 - 841 Jmol OpenAstexViewer
B 779 - 841 Jmol OpenAstexViewer
PUB 69 - 150 4JUY A 88 - 169 Jmol OpenAstexViewer
B 88 - 169 Jmol OpenAstexViewer
4OYJ A 69 - 150 Jmol OpenAstexViewer
B 69 - 150 Jmol OpenAstexViewer
C 69 - 150 Jmol OpenAstexViewer
D 69 - 150 Jmol OpenAstexViewer
E 69 - 150 Jmol OpenAstexViewer
F 69 - 150 Jmol OpenAstexViewer
G 69 - 150 Jmol OpenAstexViewer
H 69 - 150 Jmol OpenAstexViewer
I 69 - 150 Jmol OpenAstexViewer
J 69 - 150 Jmol OpenAstexViewer
K 69 - 150 Jmol OpenAstexViewer
L 69 - 150 Jmol OpenAstexViewer
M 69 - 150 Jmol OpenAstexViewer
4OYK A 69 - 150 Jmol OpenAstexViewer
B 69 - 150 Jmol OpenAstexViewer
4P09 A 69 - 150 Jmol OpenAstexViewer
4P0A A 69 - 150 Jmol OpenAstexViewer
C 69 - 150 Jmol OpenAstexViewer
4P0B A 69 - 150 Jmol OpenAstexViewer
C 69 - 150 Jmol OpenAstexViewer
5LJN A 69 - 150 Jmol OpenAstexViewer
B 69 - 150 Jmol OpenAstexViewer
PUB_1 1 - 65 4JUY A 20 - 84 Jmol OpenAstexViewer
B 20 - 84 Jmol OpenAstexViewer
4OYJ D 1 - 65 Jmol OpenAstexViewer
E 1 - 65 Jmol OpenAstexViewer
G 1 - 65 Jmol OpenAstexViewer
10 - 65 4OYJ L 10 - 65 Jmol OpenAstexViewer
2 - 65 4OYJ A 2 - 65 Jmol OpenAstexViewer
B 2 - 65 Jmol OpenAstexViewer
4P09 A 2 - 65 Jmol OpenAstexViewer
3 - 65 4P0A C 3 - 65 Jmol OpenAstexViewer
4 - 65 4OYJ C 4 - 65 Jmol OpenAstexViewer
F 4 - 65 Jmol OpenAstexViewer
4P0A A 4 - 65 Jmol OpenAstexViewer
5 - 62 4P0B C 5 - 62 Jmol OpenAstexViewer
5 - 65 4OYJ H 5 - 65 Jmol OpenAstexViewer
I 5 - 65 Jmol OpenAstexViewer
J 5 - 65 Jmol OpenAstexViewer
K 5 - 65 Jmol OpenAstexViewer
M 5 - 65 Jmol OpenAstexViewer
4P0B A 5 - 65 Jmol OpenAstexViewer
5LJN A 5 - 65 Jmol OpenAstexViewer
B 5 - 65 Jmol OpenAstexViewer
6 - 65 4OYK B 6 - 65 Jmol OpenAstexViewer
7 - 65 4OYK A 7 - 65 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.