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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PDLI5_HUMAN (Q96HC4)

Summary

This is the summary of UniProt entry PDLI5_HUMAN (Q96HC4).

Description: PDZ and LIM domain protein 5
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 596 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam PDZ 4 82
disorder n/a 29 30
disorder n/a 64 65
disorder n/a 67 69
disorder n/a 72 73
disorder n/a 77 113
disorder n/a 115 347
low_complexity n/a 143 171
Pfam DUF4749 211 305
disorder n/a 354 381
disorder n/a 387 408
Pfam LIM 420 475
Pfam LIM 479 534
Pfam LIM 538 594

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96HC4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSNYSVSLVG PAPWGFRLQG GKDFNMPLTI SSLKDGGKAA QANVRIGDVV
50
51
LSIDGINAQG MTHLEAQNKI KGCTGSLNMT LQRASAAPKP EPVPVQKGEP
100
101
KEVVKPVPIT SPAVSKVTST NNMAYNKAPR PFGSVSSPKV TSIPSPSSAF
150
151
TPAHATTSSH ASPSPVAAVT PPLFAASGLH ANANLSADQS PSALSAGKTA
200
201
VNVPRQPTVT SVCSETSQEL AEGQRRGSQG DSKQQNGPPR KHIVERYTEF
250
251
YHVPTHSDAS KKRLIEDTED WRPRTGTTQS RSFRILAQIT GTEHLKESEA
300
301
DNTKKANNSQ EPSPQLASSV ASTRSMPESL DSPTSGRPGV TSLTAAAAFK
350
351
PVGSTGVIKS PSWQRPNQGV PSTGRISNSA TYSGSVAPAN SALGQTQPSD
400
401
QDTLVQRAEH IPAGKRTPMC AHCNQVIRGP FLVALGKSWH PEEFNCAHCK
450
451
NTMAYIGFVE EKGALYCELC YEKFFAPECG RCQRKILGEV ISALKQTWHV
500
501
SCFVCVACGK PIRNNVFHLE DGEPYCETDY YALFGTICHG CEFPIEAGDM
550
551
FLEALGYTWH DTCFVCSVCC ESLEGQTFFS KKDKPLCKKH AHSVNF    
596
 

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Checksums:
CRC64:BBEAB9EDFA060736
MD5:f15dab0f6b4bb8dce146da54f64b2e93

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
LIM 420 - 475 2DAR A 28 - 83 Jmol OpenAstexViewer
PDZ 4 - 82 2UZC A 4 - 82 Jmol OpenAstexViewer
B 4 - 82 Jmol OpenAstexViewer
C 4 - 82 Jmol OpenAstexViewer
D 4 - 82 Jmol OpenAstexViewer
E 4 - 82 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.