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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: JPH4_HUMAN (Q96JJ6)

Summary

This is the summary of UniProt entry JPH4_HUMAN (Q96JJ6).

Description: Junctophilin-4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 628 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam MORN 15 34
Pfam MORN 39 60
Pfam MORN 61 82
disorder n/a 63 69
Pfam MORN 83 105
Pfam MORN 106 128
disorder n/a 121 123
disorder n/a 125 131
Pfam MORN 129 149
disorder n/a 134 137
disorder n/a 140 142
disorder n/a 147 216
low_complexity n/a 170 180
low_complexity n/a 216 246
disorder n/a 229 276
low_complexity n/a 253 272
Pfam MORN 282 304
Pfam MORN 305 327
disorder n/a 307 337
disorder n/a 360 378
low_complexity n/a 367 378
low_complexity n/a 372 406
disorder n/a 406 606
low_complexity n/a 453 467
low_complexity n/a 494 515
low_complexity n/a 528 542
low_complexity n/a 536 557
transmembrane n/a 607 627
low_complexity n/a 613 627

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96JJ6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSPGGKFDFD DGGCYVGGWE AGRAHGYGVC TGPGAQGEYS GCWAHGFESL
50
51
GVFTGPGGHS YQGHWQQGKR EGLGVERKSR WTYRGEWLGG LKGRSGVWES
100
101
VSGLRYAGLW KDGFQDGYGT ETYSDGGTYQ GQWQAGKRHG YGVRQSVPYH
150
151
QAALLRSPRR TSLDSGHSDP PTPPPPLPLP GDEGGSPASG SRGGFVLAGP
200
201
GDADGASSRK RTPAAGGFFR RSLLLSGLRA GGRRSSLGSK RGSLRSEVSS
250
251
EVGSTGPPGS EASGPPAAAP PALIEGSATE VYAGEWRADR RSGFGVSQRS
300
301
NGLRYEGEWL GNRRHGYGRT TRPDGSREEG KYKRNRLVHG GRVRSLLPLA
350
351
LRRGKVKEKV DRAVEGARRA VSAARQRQEI AAARAADALL KAVAASSVAE
400
401
KAVEAARMAK LIAQDLQPML EAPGRRPRQD SEGSDTEPLD EDSPGVYENG
450
451
LTPSEGSPEL PSSPASSRQP WRPPACRSPL PPGGDQGPFS SPKAWPEEWG
500
501
GAGAQAEELA GYEAEDEAGM QGPGPRDGSP LLGGCSDSSG SLREEEGEDE
550
551
EPLPPLRAPA GTEPEPIAML VLRGSSSRGP DAGCLTEELG EPAATERPAQ
600
601
PGAANPLVVG AVALLDLSLA FLFSQLLT                        
628
 

Show the unformatted sequence.

Checksums:
CRC64:60E7CF537FAF5D37
MD5:4c2851367daec3d1807536fe72bc2277

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;