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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LMBL3_HUMAN (Q96JM7)

Summary

This is the summary of UniProt entry LMBL3_HUMAN (Q96JM7).

Description: Lethal(3)malignant brain tumor-like protein 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 780 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 6
disorder n/a 51 86
disorder n/a 99 101
disorder n/a 149 207
low_complexity n/a 153 165
low_complexity n/a 203 213
disorder n/a 214 220
Pfam MBT 268 336
Pfam MBT 375 443
Pfam MBT 479 545
disorder n/a 531 535
disorder n/a 543 557
disorder n/a 560 563
disorder n/a 569 571
disorder n/a 580 583
disorder n/a 594 664
Pfam SAM_1 706 770

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96JM7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTESASSTSG QEFDVFSVMD WKDGVGTLPG SDLKFRVNEF GALEVITDEN
50
51
EMENVKKATA TTTWMVPTAQ EAPTSPPSSR PVFPPAYWTS PPGCPTVFSE
100
101
KTGMPFRLKD PVKVEGLQFC ENCCQYGNVD ECLSGGNYCS QNCARHIKDK
150
151
DQKEERDVEE DNEEEDPKCS RKKKPKLSLK ADTKEDGEER DDEMENKQDV
200
201
RILRGSQRAR RKRRGDSAVL KQGLPPKGKK AWCWASYLEE EKAVAVPAKL
250
251
FKEHQSFPYN KNGFKVGMKL EGVDPEHQSV YCVLTVAEVC GYRIKLHFDG
300
301
YSDCYDFWVN ADALDIHPVG WCEKTGHKLH PPKGYKEEEF NWQTYLKTCK
350
351
AQAAPKSLFE NQNITVIPSG FRVGMKLEAV DKKNPSFICV ATVTDMVDNR
400
401
FLVHFDNWDE SYDYWCEASS PHIHPVGWCK EHRRTLITPP GYPNVKHFSW
450
451
DKYLEETNSL PAPARAFKVK PPHGFQKKMK LEVVDKRNPM FIRVATVADT
500
501
DDHRVKVHFD GWNNCYDYWI DADSPDIHPV GWCSKTGHPL QPPLSPLELM
550
551
EASEHGGCST PGCKGIGHFK RARHLGPHSA ANCPYSEINL NKDRIFPDRL
600
601
SGEMPPASPS FPRNKRTDAN ESSSSPEIRD QHADDVKEDF EERTESEMRT
650
651
SHEARGAREE PTVQQAQRRS AVFLSFKSPI PCLPLRWEQQ SKLLPTVAGI
700
701
PASKVSKWST DEVSEFIQSL PGCEEHGKVF KDEQIDGEAF LLMTQTDIVK
750
751
IMSIKLGPAL KIFNSILMFK AAEKNSHNEL                      
780
 

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Checksums:
CRC64:81F92D4423E25C84
MD5:68465d268d119ea09c09397e6070ec48

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
MBT 268 - 336 1WJS A 18 - 86 Jmol OpenAstexViewer
3UT1 A 268 - 336 Jmol OpenAstexViewer
4FL6 A 268 - 336 Jmol OpenAstexViewer
B 268 - 336 Jmol OpenAstexViewer
4L59 A 268 - 336 Jmol OpenAstexViewer
375 - 442 3UT1 A 375 - 442 Jmol OpenAstexViewer
4L59 A 375 - 442 Jmol OpenAstexViewer
375 - 443 4FL6 A 375 - 443 Jmol OpenAstexViewer
B 375 - 443 Jmol OpenAstexViewer
479 - 544 4FL6 A 479 - 544 Jmol OpenAstexViewer
B 479 - 544 Jmol OpenAstexViewer
4L59 A 479 - 544 Jmol OpenAstexViewer
479 - 545 1WJQ A 18 - 84 Jmol OpenAstexViewer
3UT1 A 479 - 545 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.