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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PHAR3_HUMAN (Q96KR7)

Summary

This is the summary of UniProt entry PHAR3_HUMAN (Q96KR7).

Description: Phosphatase and actin regulator 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 559 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 70
low_complexity n/a 25 35
low_complexity n/a 76 89
disorder n/a 82 83
disorder n/a 85 366
low_complexity n/a 185 196
low_complexity n/a 228 247
coiled_coil n/a 349 369
disorder n/a 389 391
disorder n/a 401 403
disorder n/a 414 425
disorder n/a 427 429
low_complexity n/a 428 438
disorder n/a 432 439
Pfam RPEL 440 463
coiled_coil n/a 450 477
disorder n/a 452 486
disorder n/a 516 520
disorder n/a 532 559

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96KR7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAASEDGSGC LVSRGRSQSD PSVLTDSSAT SSADAGENPD EMDQTPPARP
50
51
EYLVSGIRTP PVRRNSKLAT LGRIFKPWKW RKKKNEKLKQ TTSALEKKMA
100
101
GRQGREELIK KGLLEMMEQD AESKTCNPDG GPRSVQSEPP TPKSETLTSE
150
151
DAQPGSPLAT GTDQVSLDKP LSSAAHLDDA AKMPSASSGE EADAGSLLPT
200
201
TNELSQALAG ADSLDSPPRP LERSVGQLPS PPLLPTPPPK ASSKTTKNVT
250
251
GQATLFQASS MKSADPSLRG QLSTPTGSPH LTTVHRPLPP SRVIEELHRA
300
301
LATKHRQDSF QGRESKGSPK KRLDVRLSRT SSVERGKERE EAWSFDGALE
350
351
NKRTAAKESE ENKENLIINS ELKDDLLLYQ DEEALNDSII SGTLPRKCKK
400
401
ELLAVKLRNR PSKQELEDRN IFPRRTDEER QEIRQQIEMK LSKRLSQRPA
450
451
VEELERRNIL KQRNDQTEQE ERREIKQRLT RKLNQRPTVD ELRDRKILIR
500
501
FSDYVEVAKA QDYDRRADKP WTRLSAADKA AIRKELNEYK SNEMEVHASS
550
551
KHLTRFHRP                                             
559
 

Show the unformatted sequence.

Checksums:
CRC64:E98182FBE3D25D37
MD5:3b00def3618eade4b29cc6d0421a9eef

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;