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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LRRC7_HUMAN (Q96NW7)

Summary

This is the summary of UniProt entry LRRC7_HUMAN (Q96NW7).

Description: Leucine-rich repeat-containing protein 7
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1537 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 134 145
Pfam LRR_8 138 196
low_complexity n/a 273 281
disorder n/a 408 413
disorder n/a 418 449
disorder n/a 459 469
low_complexity n/a 460 470
disorder n/a 471 480
disorder n/a 490 492
disorder n/a 512 519
disorder n/a 521 522
disorder n/a 525 529
disorder n/a 541 553
disorder n/a 555 556
disorder n/a 558 560
disorder n/a 563 564
disorder n/a 567 568
disorder n/a 577 585
disorder n/a 587 618
disorder n/a 624 646
disorder n/a 650 715
disorder n/a 717 718
disorder n/a 720 897
low_complexity n/a 789 803
low_complexity n/a 858 872
disorder n/a 899 900
disorder n/a 905 912
disorder n/a 919 932
disorder n/a 934 941
disorder n/a 969 1028
disorder n/a 1039 1066
disorder n/a 1069 1074
disorder n/a 1081 1087
disorder n/a 1090 1091
disorder n/a 1097 1100
disorder n/a 1124 1125
disorder n/a 1127 1228
disorder n/a 1231 1266
disorder n/a 1268 1271
disorder n/a 1274 1277
disorder n/a 1281 1287
disorder n/a 1289 1292
disorder n/a 1300 1303
disorder n/a 1309 1404
disorder n/a 1407 1436
disorder n/a 1443 1447
Pfam PDZ 1448 1532
low_complexity n/a 1455 1468
disorder n/a 1462 1468
disorder n/a 1475 1488
disorder n/a 1491 1497
disorder n/a 1504 1505

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96NW7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTTKRKIIGR LVPCRCFRGE EEIISVLDYS HCSLQQVPKE VFNFERTLEE
50
51
LYLDANQIEE LPKQLFNCQA LRKLSIPDND LSNLPTTIAS LVNLKELDIS
100
101
KNGVQEFPEN IKCCKCLTII EASVNPISKL PDGFTQLLNL TQLYLNDAFL
150
151
EFLPANFGRL VKLRILELRE NHLKTLPKSM HKLAQLERLD LGNNEFGELP
200
201
EVLDQIQNLR ELWMDNNALQ VLPGSIGKLK MLVYLDMSKN RIETVDMDIS
250
251
GCEALEDLLL SSNMLQQLPD SIGLLKKLTT LKVDDNQLTM LPNTIGNLSL
300
301
LEEFDCSCNE LESLPSTIGY LHSLRTLAVD ENFLPELPRE IGSCKNVTVM
350
351
SLRSNKLEFL PEEIGQMQKL RVLNLSDNRL KNLPFSFTKL KELAALWLSD
400
401
NQSKALIPLQ TEAHPETKQR VLTNYMFPQQ PRGDEDFQSD SDSFNPTLWE
450
451
EQRQQRMTVA FEFEDKKEDD ENAGKVKDLS CQAPWERGQR GITLQPARLS
500
501
GDCCTPWARC DQQIQDMPVP QNDPQLAWGC ISGLQQERSM CTPLPVAAQS
550
551
TTLPSLSGRQ VEINLKRYPT PYPEDLKNMV KSVQNLVGKP SHGVRVENSN
600
601
PTANTEQTVK EKYEHKWPVA PKEITVEDSF VHPANEMRIG ELHPSLAETP
650
651
LYPPKLVLLG KDKKESTDES EVDKTHCLNN SVSSGTYSDY SPSQASSGSS
700
701
NTRVKVGSLQ TTAKDAVHNS LWGNRIAPSF PQPLDSKPLL SQREAVPPGN
750
751
IPQRPDRLPM SDTFTDNWTD GSHYDNTGFV AEETTAENAN SNPLLSSKSR
800
801
STSSHGRRPL IRQDRIVGVP LELEQSTHRH TPETEVPPSN PWQNWTRTPS
850
851
PFEDRTAFPS KLETTPTTSP LPERKEHIKE STEIPSPFSP GVPWEYHDSN
900
901
PNRSLSNVFS QIHCRPESSK GVISISKSTE RLSPLMKDIK SNKFKKSQSI
950
951
DEIDIGTYKV YNIPLENYAS GSDHLGSHER PDKMLGPEHG MSSMSRSQSV
1000
1001
PMLDDEMLTY GSSKGPQQQK ASMTKKVYQF DQSFNPQGSV EVKAEKRIPP
1050
1051
PFQHNPEYVQ QASKNIAKDL ISPRAYRGYP PMEQMFSFSQ PSVNEDAVVN
1100
1101
AQFASQGARA GFLRRADSLV SATEMAMFRR VNEPHELPPT DRYGRPPYRG
1150
1151
GLDRQSSVTV TESQFLKRNG RYEDEHPSYQ EVKAQAGSFP VKNLTQRRPL
1200
1201
SARSYSTESY GASQTRPVSA RPTMAALLEK IPSDYNLGNY GDKPSDNSDL
1250
1251
KTRPTPVKGE ESCGKMPADW RQQLLRHIEA RRLDRNAAYK HNTVNLGMLP
1300
1301
YGGISAMHAG RSMTLNLQTK SKFDHQELPL QKTPSQQSNI LDNGQEDVSP
1350
1351
SGQWNPYPLG RRDVPPDTIT KKAGSHIQTL MGSQSLQHRS REQQPYEGNI
1400
1401
NKVTIQQFQS PLPIQIPSSQ ATRGPQPGRC LIQTKGQRSM DGYPEQFCVR
1450
1451
IEKNPGLGFS ISGGISGQGN PFKPSDKGIF VTRVQPDGPA SNLLQPGDKI
1500
1501
LQANGHSFVH MEHEKAVLLL KSFQNTVDLV IQRELTV              
1537
 

Show the unformatted sequence.

Checksums:
CRC64:1EB99AF133CD2925
MD5:4827f44ef11152ffe3377c1b42f573df

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.