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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: RBM14_HUMAN (Q96PK6)

Summary

This is the summary of UniProt entry RBM14_HUMAN (Q96PK6).

Description: RNA-binding protein 14
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 669 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam RRM_1 3 66
disorder n/a 66 67
Pfam RRM_1 81 143
disorder n/a 128 130
disorder n/a 140 175
disorder n/a 193 233
low_complexity n/a 211 224
disorder n/a 241 244
disorder n/a 258 262
disorder n/a 266 273
disorder n/a 282 287
low_complexity n/a 286 303
disorder n/a 292 294
disorder n/a 298 303
low_complexity n/a 310 327
low_complexity n/a 345 356
low_complexity n/a 367 401
low_complexity n/a 403 434
low_complexity n/a 427 457
low_complexity n/a 482 510
low_complexity n/a 518 531
disorder n/a 524 525
disorder n/a 527 528
disorder n/a 533 547
disorder n/a 551 554
disorder n/a 562 564
disorder n/a 567 590
disorder n/a 592 596
disorder n/a 608 612
disorder n/a 614 615
disorder n/a 617 640
disorder n/a 666 669

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96PK6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKIFVGNVDG ADTTPEELAA LFAPYGTVMS CAVMKQFAFV HMRENAGALR
50
51
AIEALHGHEL RPGRALVVEM SRPRPLNTWK IFVGNVSAAC TSQELRSLFE
100
101
RRGRVIECDV VKDYAFVHME KEADAKAAIA QLNGKEVKGK RINVELSTKG
150
151
QKKGPGLAVQ SGDKTKKPGA GDTAFPGTGG FSATFDYQQA FGNSTGGFDG
200
201
QARQPTPPFF GRDRSPLRRS PPRASYVAPL TAQPATYRAQ PSVSLGAAYR
250
251
AQPSASLGVG YRTQPMTAQA ASYRAQPSVS LGAPYRGQLA SPSSQSAAAS
300
301
SLGPYGGAQP SASALSSYGG QAAAASSLNS YGAQGSSLAS YGNQPSSYGA
350
351
QAASSYGVRA AASSYNTQGA ASSLGSYGAQ AASYGAQSAA SSLAYGAQAA
400
401
SYNAQPSASY NAQSAPYAAQ QAASYSSQPA AYVAQPATAA AYASQPAAYA
450
451
AQATTPMAGS YGAQPVVQTQ LNSYGAQASM GLSGSYGAQS AAAATGSYGA
500
501
AAAYGAQPSA TLAAPYRTQS SASLAASYAA QQHPQAAASY RGQPGNAYDG
550
551
AGQPSAAYLS MSQGAVANAN STPPPYERTR LSPPRASYDD PYKKAVAMSK
600
601
RYGSDRRLAE LSDYRRLSES QLSFRRSPTK SSLDYRRLPD AHSDYARYSG
650
651
SYNDYLRAAQ MHSGYQRRM                                  
669
 

Show the unformatted sequence.

Checksums:
CRC64:565C5EF51B6881FD
MD5:df2a4620f28257c1dd204dd1a498086f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RRM_1 81 - 143 2DNP A 81 - 143 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.