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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ALKB3_HUMAN (Q96Q83)

Summary

This is the summary of UniProt entry ALKB3_HUMAN (Q96Q83).

Description: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 286 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 2
disorder n/a 9 11
disorder n/a 21 22
disorder n/a 25 44
disorder n/a 65 68
Pfam 2OG-FeII_Oxy_2 89 275
disorder n/a 159 160
disorder n/a 214 232
disorder n/a 256 262

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96Q83. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEEKRRRARV QGAWAAPVKS QAIAQPATTA KSHLHQKPGQ TWKNKEHHLS
50
51
DREFVFKEPQ QVVRRAPEPR VIDREGVYEI SLSPTGVSRV CLYPGFVDVK
100
101
EADWILEQLC QDVPWKQRTG IREDITYQQP RLTAWYGELP YTYSRITMEP
150
151
NPHWHPVLRT LKNRIEENTG HTFNSLLCNL YRNEKDSVDW HSDDEPSLGR
200
201
CPIIASLSFG ATRTFEMRKK PPPEENGDYT YVERVKIPLD HGTLLIMEGA
250
251
TQADWQHRVP KEYHSREPRV NLTFRTVYPD PRGAPW               
286
 

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Checksums:
CRC64:F6563635B1F217D7
MD5:42155f433067d8ccf4c5587fcc840f3d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
2OG-FeII_Oxy_2 89 - 275 2IUW A 89 - 275 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.