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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TRPM7_HUMAN (Q96QT4)

Summary

This is the summary of UniProt entry TRPM7_HUMAN (Q96QT4).

Description: Transient receptor potential cation channel subfamily M member 7 EC=2.7.11.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1865 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam LSDAT_euk 106 371
disorder n/a 338 339
low_complexity n/a 540 554
disorder n/a 544 572
disorder n/a 575 579
disorder n/a 591 596
disorder n/a 602 608
transmembrane n/a 758 776
disorder n/a 787 791
disorder n/a 793 794
disorder n/a 796 798
Pfam Ion_trans 855 1108
transmembrane n/a 856 878
transmembrane n/a 884 902
transmembrane n/a 923 945
transmembrane n/a 957 976
transmembrane n/a 997 1016
transmembrane n/a 1078 1101
transmembrane n/a 1122 1142
Pfam TRPM_tetra 1194 1249
disorder n/a 1256 1258
disorder n/a 1300 1303
disorder n/a 1313 1315
disorder n/a 1328 1333
disorder n/a 1340 1344
disorder n/a 1347 1348
disorder n/a 1352 1362
low_complexity n/a 1385 1397
disorder n/a 1386 1391
disorder n/a 1395 1399
disorder n/a 1402 1403
disorder n/a 1405 1408
disorder n/a 1411 1429
disorder n/a 1431 1432
disorder n/a 1436 1446
disorder n/a 1448 1449
disorder n/a 1452 1467
disorder n/a 1472 1477
disorder n/a 1486 1487
disorder n/a 1489 1542
disorder n/a 1569 1572
disorder n/a 1581 1583
disorder n/a 1586 1587
Pfam Alpha_kinase 1619 1816
disorder n/a 1831 1832
disorder n/a 1837 1864

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96QT4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQKSWIEST LTKRECVYII PSSKDPHRCL PGCQICQQLV RCFCGRLVKQ
50
51
HACFTASLAM KYSDVKLGDH FNQAIEEWSV EKHTEQSPTD AYGVINFQGG
100
101
SHSYRAKYVR LSYDTKPEVI LQLLLKEWQM ELPKLVISVH GGMQKFELHP
150
151
RIKQLLGKGL IKAAVTTGAW ILTGGVNTGV AKHVGDALKE HASRSSRKIC
200
201
TIGIAPWGVI ENRNDLVGRD VVAPYQTLLN PLSKLNVLNN LHSHFILVDD
250
251
GTVGKYGAEV RLRRELEKTI NQQRIHARIG QGVPVVALIF EGGPNVILTV
300
301
LEYLQESPPV PVVVCEGTGR AADLLAYIHK QTEEGGNLPD AAEPDIISTI
350
351
KKTFNFGQNE ALHLFQTLME CMKRKELITV FHIGSDEHQD IDVAILTALL
400
401
KGTNASAFDQ LILTLAWDRV DIAKNHVFVY GQQWLVGSLE QAMLDALVMD
450
451
RVAFVKLLIE NGVSMHKFLT IPRLEELYNT KQGPTNPMLF HLVRDVKQGN
500
501
LPPGYKITLI DIGLVIEYLM GGTYRCTYTR KRFRLIYNSL GGNNRRSGRN
550
551
TSSSTPQLRK SHESFGNRAD KKEKMRHNHF IKTAQPYRPK IDTVMEEGKK
600
601
KRTKDEIVDI DDPETKRFPY PLNELLIWAC LMKRQVMARF LWQHGEESMA
650
651
KALVACKIYR SMAYEAKQSD LVDDTSEELK QYSNDFGQLA VELLEQSFRQ
700
701
DETMAMKLLT YELKNWSNST CLKLAVSSRL RPFVAHTCTQ MLLSDMWMGR
750
751
LNMRKNSWYK VILSILVPPA ILLLEYKTKA EMSHIPQSQD AHQMTMDDSE
800
801
NNFQNITEEI PMEVFKEVRI LDSNEGKNEM EIQMKSKKLP ITRKFYAFYH
850
851
APIVKFWFNT LAYLGFLMLY TFVVLVQMEQ LPSVQEWIVI AYIFTYAIEK
900
901
VREIFMSEAG KVNQKIKVWF SDYFNISDTI AIISFFIGFG LRFGAKWNFA
950
951
NAYDNHVFVA GRLIYCLNII FWYVRLLDFL AVNQQAGPYV MMIGKMVANM
1000
1001
FYIVVIMALV LLSFGVPRKA ILYPHEAPSW TLAKDIVFHP YWMIFGEVYA
1050
1051
YEIDVCANDS VIPQICGPGT WLTPFLQAVY LFVQYIIMVN LLIAFFNNVY
1100
1101
LQVKAISNIV WKYQRYHFIM AYHEKPVLPP PLIILSHIVS LFCCICKRRK
1150
1151
KDKTSDGPKL FLTEEDQKKL HDFEEQCVEM YFNEKDDKFH SGSEERIRVT
1200
1201
FERVEQMCIQ IKEVGDRVNY IKRSLQSLDS QIGHLQDLSA LTVDTLKTLT
1250
1251
AQKASEASKV HNEITRELSI SKHLAQNLID DGPVRPSVWK KHGVVNTLSS
1300
1301
SLPQGDLESN NPFHCNILMK DDKDPQCNIF GQDLPAVPQR KEFNFPEAGS
1350
1351
SSGALFPSAV SPPELRQRLH GVELLKIFNK NQKLGSSSTS IPHLSSPPTK
1400
1401
FFVSTPSQPS CKSHLETGTK DQETVCSKAT EGDNTEFGAF VGHRDSMDLQ
1450
1451
RFKETSNKIK ILSNNNTSEN TLKRVSSLAG FTDCHRTSIP VHSKQAEKIS
1500
1501
RRPSTEDTHE VDSKAALIPD WLQDRPSNRE MPSEEGTLNG LTSPFKPAMD
1550
1551
TNYYYSAVER NNLMRLSQSI PFTPVPPRGE PVTVYRLEES SPNILNNSMS
1600
1601
SWSQLGLCAK IEFLSKEEMG GGLRRAVKVQ CTWSEHDILK SGHLYIIKSF
1650
1651
LPEVVNTWSS IYKEDTVLHL CLREIQQQRA AQKLTFAFNQ MKPKSIPYSP
1700
1701
RFLEVFLLYC HSAGQWFAVE ECMTGEFRKY NNNNGDEIIP TNTLEEIMLA
1750
1751
FSHWTYEYTR GELLVLDLQG VGENLTDPSV IKAEEKRSCD MVFGPANLGE
1800
1801
DAIKNFRAKH HCNSCCRKLK LPDLKRNDYT PDKIIFPQDE PSDLNLQPGN
1850
1851
STKESESTNS VRLML                                      
1865
 

Show the unformatted sequence.

Checksums:
CRC64:BE732674D52D7485
MD5:57e66cfc876e1a0569b4ef6786cc74c3

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.