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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: H2A1A_HUMAN (Q96QV6)

Summary

This is the summary of UniProt entry H2A1A_HUMAN (Q96QV6).

Description: Histone H2A type 1-A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 131 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 19
low_complexity n/a 1 16
Pfam Histone 2 91
low_complexity n/a 7 22
disorder n/a 74 75
disorder n/a 79 82
Pfam Histone_H2A_C 92 126
disorder n/a 119 131

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96QV6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGRGKQGGK ARAKSKSRSS RAGLQFPVGR IHRLLRKGNY AERIGAGAPV
50
51
YLAAVLEYLT AEILELAGNA SRDNKKTRII PRHLQLAIRN DEELNKLLGG
100
101
VTIAQGGVLP NIQAVLLPKK TESHHHKAQS K                    
131
 

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Checksums:
CRC64:D7E5D3D43BD84D32
MD5:7c5cbe7fc897bf976cb8180113c0ce47

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Histone 14 - 91 5GSU C 15 - 92 Jmol OpenAstexViewer
5GT0 G 13 - 90 Jmol OpenAstexViewer
15 - 91 5GSU G 16 - 92 Jmol OpenAstexViewer
5GT0 C 14 - 90 Jmol OpenAstexViewer
Histone_H2A_C 92 - 119 5GSU C 93 - 120 Jmol OpenAstexViewer
G 93 - 120 Jmol OpenAstexViewer
5GT0 G 91 - 118 Jmol OpenAstexViewer
92 - 120 5GT0 C 91 - 119 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.