Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NCOA2_DANRE (Q98TW1)

Summary

This is the summary of UniProt entry NCOA2_DANRE (Q98TW1).

Description: Nuclear receptor coactivator 2 {ECO:0000303|PubMed:17583703}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1505 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 43
low_complexity n/a 54 65
coiled_coil n/a 74 94
disorder n/a 85 107
Pfam PAS 116 214
disorder n/a 183 191
disorder n/a 198 219
disorder n/a 222 224
disorder n/a 261 275
Pfam PAS_11 266 376
disorder n/a 317 319
disorder n/a 348 358
disorder n/a 364 366
disorder n/a 377 733
Pfam NCOA_u2 460 585
low_complexity n/a 510 522
Pfam SRC-1 625 705
low_complexity n/a 628 638
low_complexity n/a 655 673
Pfam DUF4927 728 803
disorder n/a 737 741
disorder n/a 755 1074
low_complexity n/a 858 870
low_complexity n/a 918 929
low_complexity n/a 947 957
low_complexity n/a 1013 1028
Pfam Nuc_rec_co-act 1061 1107
disorder n/a 1088 1352
low_complexity n/a 1185 1200
low_complexity n/a 1243 1262
low_complexity n/a 1273 1291
Pfam DUF1518 1283 1340
low_complexity n/a 1313 1326
Pfam DUF1518 1354 1410
disorder n/a 1354 1360
disorder n/a 1362 1505
low_complexity n/a 1439 1450
low_complexity n/a 1452 1464
low_complexity n/a 1470 1499

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q98TW1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSAVGENSSD PARSEAQKRK EGPSDLLGPS PKRSTEKRNR EHESKYIEEL
50
51
AELIFANFND IDNFNVKPDK CAILKETVKQ IRQIKEQEKA AAANEDEVQK
100
101
ADVSSTGQSV IDKDALGPMM LEALDGFFFV VNMEGNIVFV SENVTQYLRY
150
151
NQEELMNTSV YSILHVGDHA EFIKNLLPKS HVNGVPWSSE NPRRNSHTFN
200
201
CRMLVNPHSE AEETQDHEAQ QKYETMQCFA VSEPKSIKEE GEDFQSCLIC
250
251
VARRVPMKER PMLPTQESFT TRQDLQGKIT SLDTSLLRAS MKPGWEDLVR
300
301
RCIQRFHLQN DGDISFAKRH QQEVIRHGQA FSPIYRFSLS DGTIVSAHTK
350
351
SKLVRSSSTN EPQLYMSLHI LQREQPVCGM ASDLGNAQTM GKPMNPMSSP
400
401
NTAGSSCTPQ GQDATISSNT STFPSPGAQK EPGAMHRFGC PGTMSHSATM
450
451
QAATPQGSGY PLKLSSPSQG SPGMLSPRHR ASPGVAGSPR LPPPQFSPAG
500
501
SLHSPASMCT SSTGGNGGAG ANHGYTSSSL NALQALSECH GVSHGQSLGS
550
551
PDRKLGSPAA HSVAVSHHLI NKMSVPESFG EQNQSEQGTP GQDEGIDLPR
600
601
DEKGNLGQFG NLDGSDPQSR LRDNKSHTKL LQLLTTKTEP IESTSPPPMA
650
651
GGEPGCKDGG AGNGGMGSQG GNGSHATSLK EKHKILHRLL QNSSSPVDLA
700
701
KLTAEATGKE LCQDSAGGTA GVPELAIKQE PVSPKKKDNA LLRYLLDKDD
750
751
NVLKGKGIKM EPGEIKEEGG KMTGIKTEKT DGGYDRVEPS SELDDILDDL
800
801
QNSQPGLFTD SRPVSLPSAV DKQSIINDIL QMTGESGANM SPQQQRALQT
850
851
AVSQQNFPAP RPGQPGRAPP VRSVSLDMNM PPKGAQGQYP MMRNNNPYSI
900
901
MQQQGMMGNH AVMPNQPNMV NAGVMGNNGP RVGMQQDGWG AQGTVGSAAS
950
951
PATAAPAGQH SLPQGALHSR MVPNPATGMP MRPNSQPGPR PMLQPQMMAN
1000
1001
AQSNMDMGMA GHQFPQQQAP PNQTAPWPDS VMPIEPVPFG NQSSSMYGGS
1050
1051
QEDVLCPPAS EGPADEGALL SQLYSALKDF DGLEEIDRAL GIPALVGQAQ
1100
1101
PVEQDQFPGQ DPSMMMDQKP PMYGQQQYAS SPANMQQAGY TPMQDATFHG
1150
1151
LQGQMGQRPG YPMLRMQARP GLRPGGVVPN QPNTLRLQLQ HRLQAQQNRQ
1200
1201
PMMNQMGGVS NMNLPLRPNV PNQGTINAQM LAQRQRELLS NHLRQRQLDQ
1250
1251
QRQQQQQQQQ QRSLAMRAQG LTMPPNMAAA AAGMPGAMSN PRIPQANLQQ
1300
1301
FPYPPNYGTG LASPPPSTSP FSPGSPNLPA PQLLSHSAMH GSQMSLANQG
1350
1351
MLGSLSGQFG AVMSPQMQHS AFQFPSSGMS QQSDGGFGGA ATPQSPLMSP
1400
1401
RMGHAQSPMM QQAQGNSSFQ SSPDMNGWPQ GNINTNSMFT QQSPPQFSQQ
1450
1451
ANNNMYNGNG MNLNVSMAAN SSNMGQMGNQ MSMSSMNSGP GSGMANMGPE
1500
1501
QQKYC                                                 
1505
 

Show the unformatted sequence.

Checksums:
CRC64:88BD0A8435B14497
MD5:1f57d81b7bc097a07afab5f97d467f50

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;