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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: NKX31_HUMAN (Q99801)

Summary

This is the summary of UniProt entry NKX31_HUMAN (Q99801).

Description: Homeobox protein Nkx-3.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 234 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 133
low_complexity n/a 4 21
low_complexity n/a 39 51
low_complexity n/a 53 62
low_complexity n/a 81 95
Pfam Homeodomain 125 181
disorder n/a 154 156
coiled_coil n/a 174 194
disorder n/a 183 185
low_complexity n/a 209 223

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q99801. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLRVPEPRPG EAKAEGAAPP TPSKPLTSFL IQDILRDGAQ RQGGRTSSQR
50
51
QRDPEPEPEP EPEGGRSRAG AQNDQLSTGP RAAPEEAETL AETEPERHLG
100
101
SYLLDSENTS GALPRLPQTP KQPQKRSRAA FSHTQVIELE RKFSHQKYLS
150
151
APERAHLAKN LKLTETQVKI WFQNRRYKTK RKQLSSELGD LEKHSSLPAL
200
201
KEEAFSRASL VSVYNSYPYY PYLYCVGSWS PAFW                 
234
 

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Checksums:
CRC64:C99A0943E15B2A55
MD5:22e0264a18369cb6e6cf723580d4a710

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Homeodomain 132 - 181 2L9R A 12 - 61 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.