This is the summary of UniProt entry SMO_HUMAN (Q99835).

Description:	Smoothened homolog
Source organism:	Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length:	787 amino acids
Reference Proteome:

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This is the amino acid sequence of the UniProt sequence database entry with the accession Q99835. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.