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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PLCB3_RAT (Q99JE6)

Summary

This is the summary of UniProt entry PLCB3_RAT (Q99JE6).

Description: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 {ECO:0000305}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1234 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 5 7
disorder n/a 9 10
disorder n/a 13 16
Pfam PH_14 17 146
disorder n/a 103 105
Pfam EF-hand_like 214 308
Pfam PI-PLC-X 317 467
disorder n/a 375 378
disorder n/a 445 451
disorder n/a 454 589
low_complexity n/a 486 503
low_complexity n/a 501 513
low_complexity n/a 551 576
Pfam PI-PLC-Y 589 703
Pfam C2 725 826
disorder n/a 878 879
disorder n/a 883 992
low_complexity n/a 915 934
disorder n/a 995 1031
coiled_coil n/a 1017 1037
low_complexity n/a 1017 1028
Pfam PLC-beta_C 1029 1202
disorder n/a 1045 1046
disorder n/a 1053 1061
coiled_coil n/a 1073 1104
low_complexity n/a 1081 1094
disorder n/a 1082 1086
disorder n/a 1093 1125
disorder n/a 1132 1150
coiled_coil n/a 1144 1164
disorder n/a 1154 1156
low_complexity n/a 1154 1165
coiled_coil n/a 1169 1189
disorder n/a 1173 1176
disorder n/a 1187 1194
disorder n/a 1201 1234
low_complexity n/a 1206 1225

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q99JE6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAGARPGVHA LQLEPPTVVE TLRRGSKFIK WDEEASSRNL VTLRLDPNGF
50
51
FLYWTGPNME VDTLDISSIR DTRTGRYARL PKDPKIREVL GFGGPDTRLE
100
101
EKLMTVVAGP DPVNTTFLNF MAVQDDTVKV WSEELFKLAM NILAQNAPEH
150
151
VLRKAYTKLK LQVNQDGRIP VKNILKMFSA DKKRVETALI CGLNFNRSES
200
201
IRPDEFSLEI FERFLNKLLL RPDIDKILLE IGAKGKPYLT LEQLMDFINQ
250
251
KQRDPRLNEV LYPPLRSSQA RLLIEKYEPN KQFLERDQMS MEGFSRYLGG
300
301
EENGILPLEA LDLSMDMTQP LSAYFINSSH NTYLTAGQLA GTSSVEMYRQ
350
351
ALLWGCRCVE LDVWKGRPPE EEPFITHGFT MTTEVPLRDV LEAIAETAFK
400
401
TSPYPVILSF ENHVDSAKQQ AKMAEYCRSI FGEALLIDPL DKYPLSAGTP
450
451
LPSPQDLMGR ILVKNKKRHR PSTGVPDSSV AKRPLEQSNS ALSESSAATE
500
501
PSSPQLGSPS SDSCPGLSNG EEVGLEKTSL EPQKSLGEEG LNRGPNVLMP
550
551
DRDREDEEED EEEEETTDPK KPTTDEGTAS SEVNATEEMS TLVNYVEPVK
600
601
FKSFEASRKR NKCFEMSSFV ETKAMEQLTK SPMEFVEYNK QQLSRIYPKG
650
651
TRVDSSNYMP QLFWNVGCQL VALNFQTLDL PMQLNAGVFE YNGRSGYLLK
700
701
PEFMRRPDKS FDPFTEVIVD GIVANALRVK VISGQFLSDR KVGIYVEVDM
750
751
FGLPVDTRRK YRTRTSQGNS FNPVWDEEPF DFPKVVLPTL ASLRIAAFEE
800
801
GGRFVGHRIL PVSAIRSGYH YVCLRNEANQ PLCLPALLIY TEASDYIPDD
850
851
HQDYAEALIN PIKHVSLMDQ RAKQLAALIG ESEAQASTEM CQETPSQQQG
900
901
SQLSSNPVPN PLDDSPRWPP GPTTSPTSTS LSSPGQRDDL IASILSEVTP
950
951
TPLEELRSHK AMVKLRSRQD RDLRELHKKH QRKAVALTRR LLDGLAQARA
1000
1001
EGKCRPSSSA LSRATNVEDV KEEEKEAARQ YREFQNRQVQ SLLELREAQA
1050
1051
DAETERRLEH LKQAQQRLRE VVLDAHTTQF KRLKELNERE KKELQKILDR
1100
1101
KRNNSISEAK TREKHKKEVE LTEINRRHIT ESVNSIRRLE EAQKQRHERL
1150
1151
LAGQQQVLQQ LVEEEPKLVA QLTQECQEQR ERLPQEIRRC LLGETSEGLG
1200
1201
DGPLVACASN GHAAGSGGHQ SGADSESQEE NTQL                 
1234
 

Show the unformatted sequence.

Checksums:
CRC64:2EBD7282F052CA6A
MD5:37362754865174b242d27689c533c01d

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;