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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: CND3_HUMAN (Q9BPX3)

Summary

This is the summary of UniProt entry CND3_HUMAN (Q9BPX3).

Description: Condensin complex subunit 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1015 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 85 92
coiled_coil n/a 485 505
coiled_coil n/a 518 545
Pfam Cnd3 559 859
low_complexity n/a 624 631
disorder n/a 673 681
low_complexity n/a 723 736
low_complexity n/a 854 863
disorder n/a 901 935
disorder n/a 939 1006

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9BPX3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGAERRLLSI KEAFRLAQQP HQNQAKLVVA LSRTYRTMDD KTVFHEEFIH
50
51
YLKYVMVVYK REPAVERVIE FAAKFVTSFH QSDMEDDEEE EDGGLLNYLF
100
101
TFLLKSHEAN SNAVRFRVCL LINKLLGSMP ENAQIDDDVF DKINKAMLIR
150
151
LKDKIPNVRI QAVLALSRLQ DPKDDECPVV NAYATLIEND SNPEVRRAVL
200
201
SCIAPSAKTL PKIVGRTKDV KEAVRKLAYQ VLAEKVHMRA MSIAQRVMLL
250
251
QQGLNDRSDA VKQAMQKHLL QGWLRFSEGN ILELLHRLDV ENSSEVAVSV
300
301
LNALFSITPL SELVGLCKNN DGRKLIPVET LTPEIALYWC ALCEYLKSKG
350
351
DEGEEFLEQI LPEPVVYADY LLSYIQSIPV VNEEHRGDFS YIGNLMTKEF
400
401
IGQQLILIIK SLDTSEEGGR KKLLAVLQEI LILPTIPISL VSFLVERLLH
450
451
IIIDDNKRTQ IVTEIISEIR APIVTVGVNN DPADVRKKEL KMAEIKVKLI
500
501
EAKEALENCI TLQDFNRASE LKEEIKALED ARINLLKETE QLEIKEVHIE
550
551
KNDAETLQKC LILCYELLKQ MSISTGLSAT MNGIIESLIL PGIISIHPVV
600
601
RNLAVLCLGC CGLQNQDFAR KHFVLLLQVL QIDDVTIKIS ALKAIFDQLM
650
651
TFGIEPFKTK KIKTLHCEGT EINSDDEQES KEVEETATAK NVLKLLSDFL
700
701
DSEVSELRTG AAEGLAKLMF SGLLVSSRIL SRLILLWYNP VTEEDVQLRH
750
751
CLGVFFPVFA YASRTNQECF EEAFLPTLQT LANAPASSPL AEIDITNVAE
800
801
LLVDLTRPSG LNPQAKTSQD YQALTVHDNL AMKICNEILT SPCSPEIRVY
850
851
TKALSSLELS SHLAKDLLVL LNEILEQVKD RTCLRALEKI KIQLEKGNKE
900
901
FGDQAEAAQD ATLTTTTFQN EDEKNKEVYM TPLRGVKATQ ASKSTQLKTN
950
951
RGQRKVTVSA RTNRRCQTAE ADSESDHEVP EPESEMKMRL PRRAKTAALE
1000
1001
KSKLNLAQFL NEDLS                                      
1015
 

Show the unformatted sequence.

Checksums:
CRC64:D9ACC205C48F3AF5
MD5:1b01ea536fb7509c7dfab6842b89884b

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Cnd3 559 - 859 6IGX B 559 - 859 Show 3D Structure View in InterPro
D 559 - 859 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;