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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: RBM4_HUMAN (Q9BWF3)

Summary

This is the summary of UniProt entry RBM4_HUMAN (Q9BWF3).

Description: RNA-binding protein 4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 364 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam RRM_1 4 66
disorder n/a 76 77
Pfam RRM_1 80 142
disorder n/a 80 82
disorder n/a 147 150
Pfam zf-CCHC 160 177
low_complexity n/a 225 245
disorder n/a 255 257
disorder n/a 263 264
low_complexity n/a 281 298
disorder n/a 309 327

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9BWF3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVKLFIGNLP REATEQEIRS LFEQYGKVLE CDIIKNYGFV HIEDKTAAED
50
51
AIRNLHHYKL HGVNINVEAS KNKSKTSTKL HVGNISPTCT NKELRAKFEE
100
101
YGPVIECDIV KDYAFVHMER AEDAVEAIRG LDNTEFQGKR MHVQLSTSRL
150
151
RTAPGMGDQS GCYRCGKEGH WSKECPIDRS GRVADLTEQY NEQYGAVRTP
200
201
YTMSYGDSLY YNNAYGALDA YYKRCRAARS YEAVAAAAAS VYNYAEQTLS
250
251
QLPQVQNTAM ASHLTSTSLD PYDRHLLPTS GAAATAAAAA AAAAAVTAAS
300
301
TSYYGRDRSP LRRATAPVPT VGEGYGYGHE SELSQASAAA RNSLYDMARY
350
351
EREQYADRAR YSAF                                       
364
 

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Checksums:
CRC64:3EA1C80D4C9122A2
MD5:d3ef83a2be034099220a4745fe936da9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RRM_1 4 - 66 2DNQ A 4 - 66 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.