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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: 1433B_MOUSE (Q9CQV8)

Summary

This is the summary of UniProt entry 1433B_MOUSE (Q9CQV8).

Description: 14-3-3 protein beta/alpha
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 246 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam 14-3-3 11 231
disorder n/a 25 26
disorder n/a 32 33
disorder n/a 67 70
coiled_coil n/a 67 105
disorder n/a 72 83
disorder n/a 141 143
disorder n/a 155 156
disorder n/a 231 246

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9CQV8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY
50
51
KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL
100
101
ELLDKYLILN ATQAESKVFY LKMKGDYFRY LSEVASGENK QTTVSNSQQA
150
151
YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE
200
201
AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN    
246
 

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Checksums:
CRC64:51C366ED85B38EED
MD5:b9ce7987d41e620d02bf734636ae13d6

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
14-3-3 11 - 231 4GNT A 11 - 231 Jmol OpenAstexViewer
5F74 A 11 - 231 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.