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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CWC25_MOUSE (Q9DBF7)

Summary

This is the summary of UniProt entry CWC25_MOUSE (Q9DBF7).

Description: Pre-mRNA-splicing factor CWC25 homolog
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 416 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 3 12
Pfam Cir_N 11 47
disorder n/a 22 25
coiled_coil n/a 23 66
disorder n/a 31 32
low_complexity n/a 33 58
disorder n/a 35 44
disorder n/a 47 51
disorder n/a 55 58
Pfam CWC25 66 157
disorder n/a 106 116
disorder n/a 118 119
disorder n/a 125 127
low_complexity n/a 143 152
disorder n/a 145 146
disorder n/a 151 159
coiled_coil n/a 160 184
disorder n/a 164 411
low_complexity n/a 172 202
low_complexity n/a 251 269
low_complexity n/a 274 293
coiled_coil n/a 329 349
low_complexity n/a 356 374
disorder n/a 413 414

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9DBF7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGGGDLNLKK SWHPQTLRNV EKVWKAEQKH EAERKKIEEL QRELREERAR
50
51
EEMQRYAEDV GAVKKKEEKL DWMYQGPGGM VNRDEYLLGR PIDKYVFEKM
100
101
EEREAGCSSE TGLLPGSIFA PSGANSLLDM ASKIREDPLF IIRKKEEEKK
150
151
REVLNNPVKM KKIKELLQMS LEKKEKKKKK EKKKKHRKHK HRSSSSGGSS
200
201
SEDEQSQARS QKKMANSFPV LSKVPGYGLQ VRDSDRNRGL QGSLGEQRAI
250
251
KNNSRSRSSS PPRHASKKST KEERPRDRRS RSPSRRSRSP RPSKPHTSKV
300
301
NRKERDSPSP KKEAYQRRHA SGYTRKLSAE ELERKRQEMM ENAKWREEER
350
351
LNTLKRHARE DEREHRLERL DSRSGKFLHR MKLESASTSS LEDRVKRNIH
400
401
SLQRTSVALE KNFMRR                                     
416
 

Show the unformatted sequence.

Checksums:
CRC64:67AC732FED303C72
MD5:2aa0db0b0c8fe2d21bb877feb08ecb93

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;