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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZN350_HUMAN (Q9GZX5)

Summary

This is the summary of UniProt entry ZN350_HUMAN (Q9GZX5).

Description: Zinc finger protein 350
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 532 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam KRAB 7 48
disorder n/a 189 190
disorder n/a 195 196
Pfam zf-C2H2 206 228
Pfam zf-C2H2 234 256
Pfam zf-C2H2 262 284
Pfam zf-C2H2 290 312
Pfam zf-C2H2 318 340
Pfam zf-C2H2 346 368
Pfam zf-C2H2 374 396
Pfam zf-C2H2 402 424
disorder n/a 427 466
low_complexity n/a 508 524

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9GZX5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIQAQESITL EDVAVDFTWE EWQLLGAAQK DLYRDVMLEN YSNLVAVGYQ
50
51
ASKPDALFKL EQGEQLWTIE DGIHSGACSD IWKVDHVLER LQSESLVNRR
100
101
KPCHEHDAFE NIVHCSKSQF LLGQNHDIFD LRGKSLKSNL TLVNQSKGYE
150
151
IKNSVEFTGN GDSFLHANHE RLHTAIKFPA SQKLISTKSQ FISPKHQKTR
200
201
KLEKHHVCSE CGKAFIKKSW LTDHQVMHTG EKPHRCSLCE KAFSRKFMLT
250
251
EHQRTHTGEK PYECPECGKA FLKKSRLNIH QKTHTGEKPY ICSECGKGFI
300
301
QKGNLIVHQR IHTGEKPYIC NECGKGFIQK TCLIAHQRFH TGKTPFVCSE
350
351
CGKSCSQKSG LIKHQRIHTG EKPFECSECG KAFSTKQKLI VHQRTHTGER
400
401
PYGCNECGKA FAYMSCLVKH KRIHTREKQE AAKVENPPAE RHSSLHTSDV
450
451
MQEKNSANGA TTQVPSVAPQ TSLNISGLLA NRNVVLVGQP VVRCAASGDN
500
501
RGFAQDRNLV NAVNVVVPSV INYVLFYVTE NP                   
532
 

Show the unformatted sequence.

Checksums:
CRC64:FEF12A92F95BAC8A
MD5:58865a21a10d23e1be14d0c57121353e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;