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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: UBA5_HUMAN (Q9GZZ9)

Summary

This is the summary of UniProt entry UBA5_HUMAN (Q9GZZ9).

Description: Ubiquitin-like modifier-activating enzyme 5
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 404 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
coiled_coil n/a 5 25
disorder n/a 23 28
disorder n/a 30 36
disorder n/a 38 41
Pfam ThiF 53 310
low_complexity n/a 78 86
disorder n/a 302 309
low_complexity n/a 325 339
low_complexity n/a 343 353
disorder n/a 356 358
disorder n/a 368 370
disorder n/a 372 373
disorder n/a 379 404

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9GZZ9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAESVERLQQ RVQELERELA QERSLQVPRS GDGGGGRVRI EKMSSEVVDS
50
51
NPYSRLMALK RMGIVSDYEK IRTFAVAIVG VGGVGSVTAE MLTRCGIGKL
100
101
LLFDYDKVEL ANMNRLFFQP HQAGLSKVQA AEHTLRNINP DVLFEVHNYN
150
151
ITTVENFQHF MDRISNGGLE EGKPVDLVLS CVDNFEARMT INTACNELGQ
200
201
TWMESGVSEN AVSGHIQLII PGESACFACA PPLVVAANID EKTLKREGVC
250
251
AASLPTTMGV VAGILVQNVL KFLLNFGTVS FYLGYNAMQD FFPTMSMKPN
300
301
PQCDDRNCRK QQEEYKKKVA ALPKQEVIQE EEEIIHEDNE WGIELVSEVS
350
351
EEELKNFSGP VPDLPEGITV AYTIPKKQED SVTELTVEDS GESLEDLMAK
400
401
MKNM                                                  
404
 

Show the unformatted sequence.

Checksums:
CRC64:02F0F64FEAA1E880
MD5:0681281a1898d2e104cb3519015d3e6a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ThiF 68 - 310 5IAA A 68 - 310 Jmol OpenAstexViewer
B 68 - 310 Jmol OpenAstexViewer
5L95 A 68 - 310 Jmol OpenAstexViewer
B 68 - 310 Jmol OpenAstexViewer
69 - 310 3GUC A 69 - 310 Jmol OpenAstexViewer
B 69 - 310 Jmol OpenAstexViewer
3H8V A 69 - 310 Jmol OpenAstexViewer
70 - 310 3H8V B 70 - 310 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.