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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: XRN2_HUMAN (Q9H0D6)

Summary

This is the summary of UniProt entry XRN2_HUMAN (Q9H0D6).

Description: 5'-3' exoribonuclease 2 EC=3.1.13.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 950 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam XRN_N 1 254
disorder n/a 32 36
disorder n/a 63 71
disorder n/a 112 127
disorder n/a 132 133
disorder n/a 193 195
disorder n/a 205 217
disorder n/a 223 224
Pfam XRN_M 325 786
disorder n/a 407 508
low_complexity n/a 414 426
low_complexity n/a 467 481
low_complexity n/a 496 506
disorder n/a 670 673
disorder n/a 780 787
disorder n/a 791 803
disorder n/a 826 834
disorder n/a 842 844
disorder n/a 846 847
disorder n/a 856 884
disorder n/a 887 892
disorder n/a 895 899
disorder n/a 904 950
low_complexity n/a 913 932

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9H0D6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGVPAFFRWL SRKYPSIIVN CVEEKPKECN GVKIPVDASK PNPNDVEFDN
50
51
LYLDMNGIIH PCTHPEDKPA PKNEDEMMVA IFEYIDRLFS IVRPRRLLYM
100
101
AIDGVAPRAK MNQQRSRRFR ASKEGMEAAV EKQRVREEIL AKGGFLPPEE
150
151
IKERFDSNCI TPGTEFMDNL AKCLRYYIAD RLNNDPGWKN LTVILSDASA
200
201
PGEGEHKIMD YIRRQRAQPN HDPNTHHCLC GADADLIMLG LATHEPNFTI
250
251
IREEFKPNKP KPCGLCNQFG HEVKDCEGLP REKKGKHDEL ADSLPCAEGE
300
301
FIFLRLNVLR EYLERELTMA SLPFTFDVER SIDDWVFMCF FVGNDFLPHL
350
351
PSLEIRENAI DRLVNIYKNV VHKTGGYLTE SGYVNLQRVQ MIMLAVGEVE
400
401
DSIFKKRKDD EDSFRRRQKE KRKRMKRDQP AFTPSGILTP HALGSRNSPG
450
451
SQVASNPRQA AYEMRMQNNS SPSISPNTSF TSDGSPSPLG GIKRKAEDSD
500
501
SEPEPEDNVR LWEAGWKQRY YKNKFDVDAA DEKFRRKVVQ SYVEGLCWVL
550
551
RYYYQGCASW KWYYPFHYAP FASDFEGIAD MPSDFEKGTK PFKPLEQLMG
600
601
VFPAASGNFL PPSWRKLMSD PDSSIIDFYP EDFAIDLNGK KYAWQGVALL
650
651
PFVDERRLRA ALEEVYPDLT PEETRRNSLG GDVLFVGKHH PLHDFILELY
700
701
QTGSTEPVEV PPELCHGIQG KFSLDEEAIL PDQIVCSPVP MLRDLTQNTV
750
751
VSINFKDPQF AEDYIFKAVM LPGARKPAAV LKPSDWEKSS NGRQWKPQLG
800
801
FNRDRRPVHL DQAAFRTLGH VMPRGSGTGI YSNAAPPPVT YQGNLYRPLL
850
851
RGQAQIPKLM SNMRPQDSWR GPPPLFQQQR FDRGVGAEPL LPWNRMLQTQ
900
901
NAAFQPNQYQ MLAGPGGYPP RRDDRGGRQG YPREGRKYPL PPPSGRYNWN
950
951
                                                      
950
 

Show the unformatted sequence.

Checksums:
CRC64:763B5E0E628F97A8
MD5:cf97ea8c8d27e45860dbd6a0b4f1498a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.