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47  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RM46_HUMAN (Q9H2W6)

Summary

This is the summary of UniProt entry RM46_HUMAN (Q9H2W6).

Description: 39S ribosomal protein L46, mitochondrial
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 279 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 21 44
Pfam MRP-L46 45 155
coiled_coil n/a 91 111
disorder n/a 100 104
disorder n/a 144 146
disorder n/a 183 184
disorder n/a 187 192

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9H2W6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAPVRRTLL GVAGGWRRFE RLWAGSLSSR SLALAAAPSS NGSPWRLLGA
50
51
LCLQRPPVVS KPLTPLQEEM ASLLQQIEIE RSLYSDHELR ALDENQRLAK
100
101
KKADLHDEED EQDILLAQDL EDMWEQKFLQ FKLGARITEA DEKNDRTSLN
150
151
RKLDRNLVLL VREKFGDQDV WILPQAEWQP GETLRGTAER TLATLSENNM
200
201
EAKFLGNAPC GHYTFKFPQA MRTESNLGAK VFFFKALLLT GDFSQAGNKG
250
251
HHVWVTKDEL GDYLKPKYLA QVRRFVSDL                       
279
 

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Checksums:
CRC64:EDA966D758715378
MD5:133eb445e0e3bdfb3ff405511afd3cb6

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
MRP-L46 145 - 155 3J7Y e 101 - 111 Show 3D Structure View in InterPro
45 - 155 3J9M e 45 - 155 Show 3D Structure View in InterPro
5OOL e 45 - 155 Show 3D Structure View in InterPro
5OOM e 45 - 155 Show 3D Structure View in InterPro
6I9R e 45 - 155 Show 3D Structure View in InterPro
6NU2 e 45 - 155 Show 3D Structure View in InterPro
6NU3 e 45 - 155 Show 3D Structure View in InterPro
6VLZ e 45 - 155 Show 3D Structure View in InterPro
6VMI e 45 - 155 Show 3D Structure View in InterPro
6ZM5 e 45 - 155 Show 3D Structure View in InterPro
6ZM6 e 45 - 155 Show 3D Structure View in InterPro
6ZS9 e 45 - 155 Show 3D Structure View in InterPro
6ZSA e 45 - 155 Show 3D Structure View in InterPro
6ZSB e 45 - 155 Show 3D Structure View in InterPro
6ZSC e 45 - 155 Show 3D Structure View in InterPro
6ZSD e 45 - 155 Show 3D Structure View in InterPro
6ZSE e 45 - 155 Show 3D Structure View in InterPro
6ZSG e 45 - 155 Show 3D Structure View in InterPro
7A5F e3 45 - 155 Show 3D Structure View in InterPro
7A5G e3 45 - 155 Show 3D Structure View in InterPro
7A5H e 45 - 155 Show 3D Structure View in InterPro
7A5I e3 45 - 155 Show 3D Structure View in InterPro
7A5J e 45 - 155 Show 3D Structure View in InterPro
7A5K e3 45 - 155 Show 3D Structure View in InterPro
7L08 e 45 - 155 Show 3D Structure View in InterPro
7L20 e 45 - 155 Show 3D Structure View in InterPro
7O9K e 45 - 155 Show 3D Structure View in InterPro
7O9M e 45 - 155 Show 3D Structure View in InterPro
7ODR e 45 - 155 Show 3D Structure View in InterPro
7ODS e 45 - 155 Show 3D Structure View in InterPro
7ODT e 45 - 155 Show 3D Structure View in InterPro
7OF0 e 45 - 155 Show 3D Structure View in InterPro
7OF2 e 45 - 155 Show 3D Structure View in InterPro
7OF3 e 45 - 155 Show 3D Structure View in InterPro
7OF4 e 45 - 155 Show 3D Structure View in InterPro
7OF5 e 45 - 155 Show 3D Structure View in InterPro
7OF6 e 45 - 155 Show 3D Structure View in InterPro
7OF7 e 45 - 155 Show 3D Structure View in InterPro
7OG4 e 45 - 155 Show 3D Structure View in InterPro
7OI7 e 45 - 155 Show 3D Structure View in InterPro
7OI8 e 45 - 155 Show 3D Structure View in InterPro
7OI9 e 45 - 155 Show 3D Structure View in InterPro
7OIA e 45 - 155 Show 3D Structure View in InterPro
7OIB e 45 - 155 Show 3D Structure View in InterPro
7OIC e 45 - 155 Show 3D Structure View in InterPro
7OID e 45 - 155 Show 3D Structure View in InterPro
7OIE e 45 - 155 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;