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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MLP3A_HUMAN (Q9H492)

Summary

This is the summary of UniProt entry MLP3A_HUMAN (Q9H492).

Description: Microtubule-associated proteins 1A/1B light chain 3A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 121 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 5
disorder n/a 7 8
Pfam Atg8 15 120
disorder n/a 18 19

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9H492. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPSDRPFKQR RSFADRCKEV QQIRDQHPSK IPVIIERYKG EKQLPVLDKT
50
51
KFLVPDHVNM SELVKIIRRR LQLNPTQAFF LLVNQHSMVS VSTPIADIYE
100
101
QEKDEDGFLY MVYASQETFG F                               
121
 

Show the unformatted sequence.

Checksums:
CRC64:48C1FBE8F7892AF3
MD5:da98ef7a8ef2b09b3ac8af37012cf5c5

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Atg8 15 - 116 3ECI A 15 - 116 Jmol OpenAstexViewer
B 15 - 116 Jmol OpenAstexViewer
15 - 119 3WAL A 19 - 123 Jmol OpenAstexViewer
3WAN A 31 - 135 Jmol OpenAstexViewer
15 - 120 3WAN B 31 - 136 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.