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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MOB1A_HUMAN (Q9H8S9)

Summary

This is the summary of UniProt entry MOB1A_HUMAN (Q9H8S9).

Description: MOB kinase activator 1A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 216 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam Mob1_phocein 31 204

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9H8S9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSFLFSSRSS KTFKPKKNIP EGSHQYELLK HAEATLGSGN LRQAVMLPEG
50
51
EDLNEWIAVN TVDFFNQINM LYGTITEFCT EASCPVMSAG PRYEYHWADG
100
101
TNIKKPIKCS APKYIDYLMT WVQDQLDDET LFPSKIGVPF PKNFMSVAKT
150
151
ILKRLFRVYA HIYHQHFDSV MQLQEEAHLN TSFKHFIFFV QEFNLIDRRE
200
201
LAPLQELIEK LGSKDR                                     
216
 

Show the unformatted sequence.

Checksums:
CRC64:58043AECAD1F5987
MD5:5c1ae7ee981afba5802de681d6dd7540

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Mob1_phocein 33 - 204 1PI1 A 12 - 183 Jmol OpenAstexViewer
40 - 204 4JIZ A 19 - 183 Jmol OpenAstexViewer
41 - 204 4J1V A 41 - 204 Jmol OpenAstexViewer
C 41 - 204 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.