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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NHEJ1_HUMAN (Q9H9Q4)

Summary

This is the summary of UniProt entry NHEJ1_HUMAN (Q9H9Q4).

Description: Non-homologous end-joining factor 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 299 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam XLF 12 182
disorder n/a 227 252
disorder n/a 254 255
disorder n/a 257 295
disorder n/a 297 299

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9H9Q4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEELEQGLLM QPWAWLQLAE NSLLAKVFIT KQGYALLVSD LQQVWHEQVD
50
51
TSVVSQRAKE LNKRLTAPPA AFLCHLDNLL RPLLKDAAHP SEATFSCDCV
100
101
ADALILRVRS ELSGLPFYWN FHCMLASPSL VSQHLIRPLM GMSLALQCQV
150
151
RELATLLHMK DLEIQDYQES GATLIRDRLK TEPFEENSFL EQFMIEKLPE
200
201
ACSIGDGKPF VMNLQDLYMA VTTQEVQVGQ KHQGAGDPHT SNSASLQGID
250
251
SQCVNQPEQL VSSAPTLSAP EKESTGTSGP LQRPQLSKVK RKKPRGLFS 
299
 

Show the unformatted sequence.

Checksums:
CRC64:BC5C68076A5E7A96
MD5:2689d36cad75073f25589afc62062a7f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
XLF 12 - 182 2QM4 A 12 - 182 Jmol OpenAstexViewer
B 12 - 182 Jmol OpenAstexViewer
C 12 - 182 Jmol OpenAstexViewer
D 12 - 182 Jmol OpenAstexViewer
2R9A A 12 - 182 Jmol OpenAstexViewer
B 12 - 182 Jmol OpenAstexViewer
3Q4F A 12 - 182 Jmol OpenAstexViewer
B 12 - 182 Jmol OpenAstexViewer
E 12 - 182 Jmol OpenAstexViewer
F 12 - 182 Jmol OpenAstexViewer
3RWR D 12 - 182 Jmol OpenAstexViewer
E 512 - 682 Jmol OpenAstexViewer
H 12 - 182 Jmol OpenAstexViewer
I 512 - 682 Jmol OpenAstexViewer
L 12 - 182 Jmol OpenAstexViewer
M 512 - 682 Jmol OpenAstexViewer
O 12 - 182 Jmol OpenAstexViewer
Q 512 - 682 Jmol OpenAstexViewer
S 12 - 182 Jmol OpenAstexViewer
T 12 - 182 Jmol OpenAstexViewer
W 512 - 682 Jmol OpenAstexViewer
X 512 - 682 Jmol OpenAstexViewer
3SR2 C 12 - 182 Jmol OpenAstexViewer
D 12 - 182 Jmol OpenAstexViewer
G 12 - 182 Jmol OpenAstexViewer
H 12 - 182 Jmol OpenAstexViewer
3W03 A 12 - 182 Jmol OpenAstexViewer
B 12 - 182 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.