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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NMNA1_HUMAN (Q9HAN9)

Summary

This is the summary of UniProt entry NMNA1_HUMAN (Q9HAN9).

Description: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 {ECO:0000305} EC=2.7.7.1 EC=2.7.7.18
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 279 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam CTP_transf_like 12 229
disorder n/a 107 142
disorder n/a 278 279

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9HAN9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MENSEKTEVV LLACGSFNPI TNMHLRLFEL AKDYMNGTGR YTVVKGIISP
50
51
VGDAYKKKGL IPAYHRVIMA ELATKNSKWV EVDTWESLQK EWKETLKVLR
100
101
HHQEKLEASD CDHQQNSPTL ERPGRKRKWT ETQDSSQKKS LEPKTKAVPK
150
151
VKLLCGADLL ESFAVPNLWK SEDITQIVAN YGLICVTRAG NDAQKFIYES
200
201
DVLWKHRSNI HVVNEWIAND ISSTKIRRAL RRGQSIRYLV PDLVQEYIEK
250
251
HNLYSSESED RNAGVILAPL QRNTAEAKT                       
279
 

Show the unformatted sequence.

Checksums:
CRC64:740DE872CD9C22E7
MD5:eafd05b6fd94e9a2d915611531d2d0cf

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CTP_transf_like 12 - 229 1GZU A 12 - 229 Jmol OpenAstexViewer
B 12 - 229 Jmol OpenAstexViewer
C 12 - 229 Jmol OpenAstexViewer
1KKU A 12 - 229 Jmol OpenAstexViewer
1KQN A 12 - 229 Jmol OpenAstexViewer
B 12 - 229 Jmol OpenAstexViewer
C 12 - 229 Jmol OpenAstexViewer
D 12 - 229 Jmol OpenAstexViewer
E 12 - 229 Jmol OpenAstexViewer
F 12 - 229 Jmol OpenAstexViewer
1KQO A 12 - 229 Jmol OpenAstexViewer
B 12 - 229 Jmol OpenAstexViewer
C 12 - 229 Jmol OpenAstexViewer
D 12 - 229 Jmol OpenAstexViewer
E 12 - 229 Jmol OpenAstexViewer
F 12 - 229 Jmol OpenAstexViewer
1KR2 A 12 - 229 Jmol OpenAstexViewer
B 12 - 229 Jmol OpenAstexViewer
C 12 - 229 Jmol OpenAstexViewer
D 12 - 229 Jmol OpenAstexViewer
E 12 - 229 Jmol OpenAstexViewer
F 12 - 229 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.