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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GCN2_SCHPO (Q9HGN1)

Summary

This is the summary of UniProt entry GCN2_SCHPO (Q9HGN1).

Description: eIF-2-alpha kinase GCN2 {ECO:0000312|PomBase:SPBC36B7.09}
Source organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (NCBI taxonomy ID 284812)
Length: 1576 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
coiled_coil n/a 4 24
Pfam RWD 12 124
low_complexity n/a 96 108
coiled_coil n/a 165 185
disorder n/a 180 203
low_complexity n/a 193 210
Pfam Pkinase 277 510
Pfam Pkinase 556 665
low_complexity n/a 556 569
disorder n/a 632 633
low_complexity n/a 632 645
disorder n/a 673 714
low_complexity n/a 695 709
Pfam Pkinase 707 919
disorder n/a 802 809
disorder n/a 811 813
low_complexity n/a 872 888
disorder n/a 910 915
Pfam tRNA-synt_His 989 1295
transmembrane n/a 1284 1303
disorder n/a 1316 1319
Pfam HGTP_anticodon2 1326 1575
disorder n/a 1398 1402

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9HGN1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDAAKRLELC KEIQENEIEA LKAIFMDDFE ELKVRNAWNV TNGHVYCIHL
50
51
CSRSANSKSI AKLDLCIELG RSYPYVKPVI KLQNGENVLN SQIRFLLDKL
100
101
DTKAKDLLGE EMIFELASIV QDYLNDWQSD LSSQFASLEE ERAVQLKHDR
150
151
ERAEVDLQLR LKREKDALFE EEQTLQNKIQ DELQRRSYET PQSSSKKKTN
200
201
SKETTSLETL PTSIYFDCSI SVRDCHDSLV TFNRVLPLYT ISHSNLSTLT
250
251
LVKPESKEIS LQDCVFLLRT VRISTPYWST EDGKREIQEL EYELESLKVI
300
301
RHDLLASIYE YQLERETRGY GWRLYVLQEY SPKFTLFSLL QTVLTLDVET
350
351
VRAFSNNILE GLAELHRLGI SHKSLHLDNV VLFHSGHRTF AKLMDFGFTR
400
401
TLRDMNASHP FNINSQSITN ILPEGLYPPE VSESSFAAAS RKTDIWCFGL
450
451
LVLQMLCGAH VLNKFSSLKL IMTHVIPLLP GSYQDLVRRC LMRDSRKRPS
500
501
AIDLLSSHVI RLGTAVLPPV EQGTFSKSAR PSYGGQQDGI IDLLYRKSVS
550
551
RYETDFEELE FLGRGGFGEV VKVKNRIDGR FYAVKKLVLL SDDKENSRIL
600
601
REVMTLSRLH HEHVVRYYTA WVETEANDTV TEIISSDSES LSQSLNMAVD
650
651
FRQSSSLPAD KLSSLDIHFE DDYNSSADEE DPEASDISFQ YSNTSDKEGS
700
701
SDKDSSIEEA SSVKTQENGL NATLYIQMEY CEKLSLQDII RDKIPVDEMW
750
751
RLFRQILEAL AYIHSRGMMH RDLKPGNIFL DENRNVKLGD FGLATENENY
800
801
QDNNDKWKNR QSADEDLTTG VGTALYVAPE LLSRRNGVRY DAKVDMYSLG
850
851
IILFEMCMTF STSMERIRII DTIRSPSISF PSTFPFSRAS HEFKVIHCLL
900
901
QHDPTKRPSS QELLESEAIP PKVGEEFIQE GLRLLSNPNT PYYLKLLKVL
950
951
FGQVPDRHKD FTYDFNLSEE SGVLSKVSDR GWDSLLACLV RDHVVKVFRR
1000
1001
HGAKERESHI LFPKSSQYDK DQASVSLLDK NGTLLQLPYD TVLPYARNVA
1050
1051
RNAVEEEKTY LISDVFREAK GGGRPKAIKE ISFDITTNSD NLDWYDAETI
1100
1101
KALDEVLTEI PSLTESCILI NHADILSSIL DYLQVSKDKR RMATHILGQI
1150
1151
NQRLTLSQVR NQLRIESLVP STTLDDLSLF DFRENYEEGA SKLRKIFGKE
1200
1201
MPQKMRTALN YMERVVKLLR ALKISHQLYF MPLCVYNFEF YDGGLMFQAI
1250
1251
NLAEKSELIC AGGRYDKLVR FFDPPLMRTA RKKHVVGICF ALEKLVFSML
1300
1301
RYIRFHNSKQ SSKHSPSPTL KSVGPWAPRR VDVLVTSIGK DSILEKCSLL
1350
1351
QELWALNIQA DIVLRGASSL EEIVTHYRSE GINWVLVVRQ KNTQMEHSVK
1400
1401
ARNILKNEDD EIRFDEVGMW LLGEINERKR NESMLQSKRI LDSAQQDVAK
1450
1451
FVDTSQSNLD VQLISLKDVN DRKYKWKHKQ NAMNKVYDLV QSAIRESSED
1500
1501
AIALAVDCDS EAMEKLRSTT TLDEESWKRL IESCPASQRE YMQRLQKKLV
1550
1551
TLAEQDKKRV WICSFRTNEI YLYGLK                          
1576
 

Show the unformatted sequence.

Checksums:
CRC64:97A97E1025C37087
MD5:a89c45831f5b1286f3ae0269d1a94ed3

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;