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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FMR1_DROME (Q9NFU0)

Summary

This is the summary of UniProt entry FMR1_DROME (Q9NFU0).

Description: Synaptic functional regulator FMR1 {ECO:0000305}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 684 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Tudor_FRX1 4 51
Pfam KH_9 125 209
Pfam KH_1 223 284
Pfam KH_1 286 361
disorder n/a 331 332
Pfam FXMRP1_C_core 362 490
coiled_coil n/a 369 389
disorder n/a 377 684
low_complexity n/a 418 441
low_complexity n/a 473 507
low_complexity n/a 539 557
low_complexity n/a 561 571
low_complexity n/a 567 592
low_complexity n/a 598 616
low_complexity n/a 625 647
low_complexity n/a 648 659

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9NFU0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEDLLVEVRL DNGAYYKGQV TAVADDGIFV DVDGVPESMK YPFVNVRLPP
50
51
EETVEVAAPI FEEGMEVEVF TRTNDRETCG WWVGIIKMRK AEIYAVAYIG
100
101
FETSYTEICE LGRLRAKNSN PPITAKTFYQ FTLPVPEELR EEAQKDGIHK
150
151
EFQRTIDAGV CNYSRDLDAL IVISKFEHTQ KRASMLKDMH FRNLSQKVML
200
201
LKRTEEAARQ LETTKLMSRG NYVEEFRVRD DLMGLAIGSH GSNIQAARTV
250
251
DGVTNIELEE KSCTFKISGE TEESVQRARA MLEYAEEFFQ VPRELVGKVI
300
301
GKNGRIIQEI VDKSGVFRIK VSAIAGDDEQ DQNIPRELAH VPFVFIGTVE
350
351
SIANAKVLLE YHLSHLKEVE QLRQEKMEID QQLRAIQESS MGSTQSFPVT
400
401
RRSERGYSSD IESVRSMRGG GGGQRGRVRG RGGGGPGGGN GLNQRYHNNR
450
451
RDEDDYNSRG DHQRDQQRGY NDRGGGDNTG SYRGGGGGAG GPGNNRRGGI
500
501
NRRPPRNDQQ NGRDYQHHNH TTEEVRETRE MSSVERADSN SSYEGSSRRR
550
551
RRQKNNNGPS NTNGAVANNN NKPQSAQQPQ QQQPPAPGNK AALNAGDASK
600
601
QNSGNANAAG GASKPKDASR NGDKQQAGTQ QQQPSQVQQQ QAAQQQQPKP
650
651
RRNKNRSNNH TDQPSGQQQL AENVKKEGLV NGTS                 
684
 

Show the unformatted sequence.

Checksums:
CRC64:973489A73B97F1FE
MD5:8110c21cea11ff1e03c17c7aa623a62d

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;