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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SH22A_HUMAN (Q9NP31)

Summary

This is the summary of UniProt entry SH22A_HUMAN (Q9NP31).

Description: SH2 domain-containing protein 2A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 389 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 19 22
disorder n/a 37 38
disorder n/a 42 58
disorder n/a 60 64
Pfam SH2 95 170
disorder n/a 179 296
low_complexity n/a 241 256
disorder n/a 298 389
low_complexity n/a 348 359

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9NP31. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEFPLAQICP QGSHEAPIPT FSTFQITDMT RRSCQNLGYT AASPQAPEAA
50
51
SNTGNAERAE EVPGEGSLFL QAETRAWFQK TQAHWLLQHG AAPAWFHGFI
100
101
TRREAERLLE PKPQGCYLVR FSESAVTFVL TYRSRTCCRH FLLAQLRDGR
150
151
HVVLGEDSAH ARLQDLLLHY TAHPLSPYGE TLTEPLARQT PEPAGLSLRT
200
201
EESNFGSKSQ DPNPQYSPII KQGQAPVPMQ KEGAGEKEPS QLLRPKPPIP
250
251
AKPQLPPEVY TIPVPRHRPA PRPKPSNPIY NEPDEPIAFY AMGRGSPGEA
300
301
PSNIYVEVED EGLPATLGHP VLRKSWSRPV PGGQNTGGSQ LHSENSVIGQ
350
351
GPPLPHQPPP AWRHTLPHNL SRQVLQDRGQ AWLPLGPPQ            
389
 

Show the unformatted sequence.

Checksums:
CRC64:986670BE084072CB
MD5:ef376470d9ba121a9feee89e28a2837c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.