Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ANM8_HUMAN (Q9NR22)

Summary

This is the summary of UniProt entry ANM8_HUMAN (Q9NR22).

Description: Protein arginine N-methyltransferase 8 EC=2.1.1.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 394 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 12 14
disorder n/a 18 43
low_complexity n/a 27 38
disorder n/a 48 49
disorder n/a 51 52
disorder n/a 56 64
Pfam PrmA 102 200
low_complexity n/a 128 135
low_complexity n/a 165 178

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9NR22. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGMKHSSRCL LLRRKMAENA AESTEVNSPP SQPPQPVVPA KPVQCVHHVS
50
51
TQPSCPGRGK MSKLLNPEEM TSRDYYFDSY AHFGIHEEML KDEVRTLTYR
100
101
NSMYHNKHVF KDKVVLDVGS GTGILSMFAA KAGAKKVFGI ECSSISDYSE
150
151
KIIKANHLDN IITIFKGKVE EVELPVEKVD IIISEWMGYC LFYESMLNTV
200
201
IFARDKWLKP GGLMFPDRAA LYVVAIEDRQ YKDFKIHWWE NVYGFDMTCI
250
251
RDVAMKEPLV DIVDPKQVVT NACLIKEVDI YTVKTEELSF TSAFCLQIQR
300
301
NDYVHALVTY FNIEFTKCHK KMGFSTAPDA PYTHWKQTVF YLEDYLTVRR
350
351
GEEIYGTISM KPNAKNVRDL DFTVDLDFKG QLCETSVSND YKMR      
394
 

Show the unformatted sequence.

Checksums:
CRC64:44B55438D16394CD
MD5:7b2b122ecfcca744b5d6bed0eb708db6

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PrmA 102 - 200 4X41 A 102 - 200 Jmol OpenAstexViewer
B 102 - 200 Jmol OpenAstexViewer
5DST A 102 - 200 Jmol OpenAstexViewer
B 102 - 200 Jmol OpenAstexViewer
C 102 - 200 Jmol OpenAstexViewer
D 102 - 200 Jmol OpenAstexViewer
E 102 - 200 Jmol OpenAstexViewer
F 102 - 200 Jmol OpenAstexViewer
G 102 - 200 Jmol OpenAstexViewer
H 102 - 200 Jmol OpenAstexViewer
I 102 - 200 Jmol OpenAstexViewer
J 102 - 200 Jmol OpenAstexViewer
K 102 - 200 Jmol OpenAstexViewer
L 102 - 200 Jmol OpenAstexViewer
M 102 - 200 Jmol OpenAstexViewer
N 102 - 200 Jmol OpenAstexViewer
O 102 - 200 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.