Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MAT2B_HUMAN (Q9NZL9)

Summary

This is the summary of UniProt entry MAT2B_HUMAN (Q9NZL9).

Description: Methionine adenosyltransferase 2 subunit beta
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 334 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam RmlD_sub_bind 29 324
disorder n/a 104 108
disorder n/a 112 114
disorder n/a 151 152
disorder n/a 280 283

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9NZL9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVGREKELSI HFVPGSCRLV EEEVNIPNRR VLVTGATGLL GRAVHKEFQQ
50
51
NNWHAVGCGF RRARPKFEQV NLLDSNAVHH IIHDFQPHVI VHCAAERRPD
100
101
VVENQPDAAS QLNVDASGNL AKEAAAVGAF LIYISSDYVF DGTNPPYREE
150
151
DIPAPLNLYG KTKLDGEKAV LENNLGAAVL RIPILYGEVE KLEESAVTVM
200
201
FDKVQFSNKS ANMDHWQQRF PTHVKDVATV CRQLAEKRML DPSIKGTFHW
250
251
SGNEQMTKYE MACAIADAFN LPSSHLRPIT DSPVLGAQRP RNAQLDCSKL
300
301
ETLGIGQRTP FRIGIKESLW PFLIDKRWRQ TVFH                 
334
 

Show the unformatted sequence.

Checksums:
CRC64:6AAA5381BAF3F65F
MD5:7f4d2b129d44429a4ae8e8e467d484e9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RmlD_sub_bind 29 - 324 2YDX A 29 - 324 Jmol OpenAstexViewer
B 29 - 324 Jmol OpenAstexViewer
C 29 - 324 Jmol OpenAstexViewer
D 29 - 324 Jmol OpenAstexViewer
E 29 - 324 Jmol OpenAstexViewer
2YDY A 29 - 324 Jmol OpenAstexViewer
4KTT E 18 - 313 Jmol OpenAstexViewer
4KTV E 18 - 313 Jmol OpenAstexViewer
F 18 - 313 Jmol OpenAstexViewer
4NDN E 18 - 313 Jmol OpenAstexViewer
F 18 - 313 Jmol OpenAstexViewer
31 - 324 4KTT F 20 - 313 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.