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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KLRF1_HUMAN (Q9NZS2)

Summary

This is the summary of UniProt entry KLRF1_HUMAN (Q9NZS2).

Description: Killer cell lectin-like receptor subfamily F member 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 231 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 12 13
transmembrane n/a 39 62
low_complexity n/a 50 61
Pfam Lectin_C 131 231

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9NZS2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQDEERYMTL NVQSKKRSSA QTSQLTFKDY SVTLHWYKIL LGISGTVNGI
50
51
LTLTLISLIL LVSQGVLLKC QKGSCSNATQ YEDTGDLKVN NGTRRNISNK
100
101
DLCASRSADQ TVLCQSEWLK YQGKCYWFSN EMKSWSDSYV YCLERKSHLL
150
151
IIHDQLEMAF IQKNLRQLNY VWIGLNFTSL KMTWTWVDGS PIDSKIFFIK
200
201
GPAKENSCAA IKESKIFSET CSSVFKWICQ Y                    
231
 

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Checksums:
CRC64:A2F7BE6D4341AFDE
MD5:d33f718d66f404d73fd62169881beb0d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;