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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: SLAI2_HUMAN (Q9P270)

Summary

This is the summary of UniProt entry SLAI2_HUMAN (Q9P270).

Description: SLAIN motif-containing protein 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 581 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 100
coiled_coil n/a 7 34
low_complexity n/a 13 31
low_complexity n/a 52 64
low_complexity n/a 75 85
low_complexity n/a 97 106
disorder n/a 102 120
low_complexity n/a 116 134
disorder n/a 123 124
Pfam SLAIN 130 581
disorder n/a 131 137
disorder n/a 182 184
disorder n/a 192 200
low_complexity n/a 195 210
disorder n/a 202 217
low_complexity n/a 205 219
disorder n/a 220 575
low_complexity n/a 250 266
low_complexity n/a 296 313
low_complexity n/a 340 367
disorder n/a 579 580

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9P270. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEDVNSNVNA DQEVRKLQEL VKKLEKQNEQ LRSRSGAVQG AGSLGPGSPV
50
51
RAGASIPSSG AASPRGFPLG LSAKSGGGPG SGPRRTSSEE LRDATSLLAA
100
101
GEGGLLDEVE PLRPDELERL SGWEEEEESW LYSSPKKKLT PMQKSVSPLV
150
151
WCRQVLDYPS PDVECAKKSL IHKLDQTMSA LKRQNLYNNP FNSMSYTSPY
200
201
SPNASSPYSS GFNSPSSTPV RPPIVKQLIL PGNSGNLKSS DRNPPLSPQS
250
251
SIDSELSASE LDEDSIGSNY KLNDVTDVQI LARMQEESLR QEYAATTSRR
300
301
SSGSSCNSTR RGTFSDQELD AQSLDDEDDN MHHAVYPAVN RFSPSPRNSP
350
351
RPSPKQSPRN SPRSRSPARG IEYSRVSPQP MISRLQQPRL SLQGHPTDLQ
400
401
TSNVKNEEKL RRSLPNLSRT SNTQVDSVKS SRSDSNFQVP NGGIPRMQPQ
450
451
ASAIPSPGKF RSPAAPSPLA LRQPVKAFSN HGSGSPGSQE ITQLTQTTSS
500
501
PGPPMVQSTV SANPPSNINS ATLTRPAGTT AMRSGLPRPS APSAGGIPVP
550
551
RSKLAQPVRR SLPAPKTYGS MKDDSWKDGC Y                    
581
 

Show the unformatted sequence.

Checksums:
CRC64:44B10B1BBD555B26
MD5:897eca688512c71acaea6266d8b0a725

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
SLAIN 574 - 581 3RDV E 574 - 581 Show 3D Structure View in InterPro
F 574 - 581 Show 3D Structure View in InterPro
H 574 - 581 Show 3D Structure View in InterPro
575 - 581 3RDV G 575 - 581 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;