Summary
This is the summary of UniProt entry SI1L2_HUMAN (Q9P2F8).
| Description: | Signal-induced proliferation-associated 1-like protein 2 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 1722 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 29 |
| disorder | n/a | 32 | 42 |
| disorder | n/a | 44 | 83 |
| low_complexity | n/a | 57 | 70 |
| disorder | n/a | 94 | 95 |
| disorder | n/a | 108 | 132 |
| low_complexity | n/a | 117 | 133 |
| disorder | n/a | 150 | 162 |
| disorder | n/a | 167 | 168 |
| disorder | n/a | 171 | 173 |
| disorder | n/a | 175 | 178 |
| disorder | n/a | 182 | 183 |
| disorder | n/a | 185 | 193 |
| disorder | n/a | 195 | 196 |
| disorder | n/a | 279 | 280 |
| disorder | n/a | 350 | 397 |
| disorder | n/a | 422 | 428 |
| low_complexity | n/a | 431 | 448 |
| disorder | n/a | 457 | 463 |
| Pfam | Rap_GAP | 624 | 806 |
| disorder | n/a | 624 | 626 |
| Pfam | PDZ | 950 | 1022 |
| disorder | n/a | 1058 | 1062 |
| disorder | n/a | 1065 | 1101 |
| low_complexity | n/a | 1093 | 1102 |
| disorder | n/a | 1103 | 1246 |
| low_complexity | n/a | 1119 | 1137 |
| low_complexity | n/a | 1219 | 1237 |
| disorder | n/a | 1253 | 1255 |
| disorder | n/a | 1258 | 1260 |
| disorder | n/a | 1269 | 1271 |
| disorder | n/a | 1284 | 1285 |
| disorder | n/a | 1294 | 1316 |
| disorder | n/a | 1330 | 1358 |
| low_complexity | n/a | 1337 | 1357 |
| low_complexity | n/a | 1357 | 1366 |
| disorder | n/a | 1369 | 1375 |
| disorder | n/a | 1378 | 1387 |
| disorder | n/a | 1398 | 1442 |
| low_complexity | n/a | 1404 | 1418 |
| Pfam | SPAR_C | 1419 | 1666 |
| low_complexity | n/a | 1494 | 1507 |
| disorder | n/a | 1495 | 1496 |
| disorder | n/a | 1504 | 1505 |
| disorder | n/a | 1524 | 1536 |
| disorder | n/a | 1559 | 1562 |
| low_complexity | n/a | 1587 | 1598 |
| disorder | n/a | 1625 | 1631 |
| disorder | n/a | 1635 | 1656 |
| coiled_coil | n/a | 1658 | 1706 |
| disorder | n/a | 1683 | 1684 |
| disorder | n/a | 1690 | 1698 |
| disorder | n/a | 1700 | 1701 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9P2F8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSDPRQSQEE KHKLGRASSK FKDPPRIMQS DDYFARKFKA INGNMGPTTS
50 51
LNASNSNETG GGGPANGTPA VPKMGVRARV SEWPPKKDCS KELTCKALWE
100 101
SRSQTSYESI TSVLQNGQSD QSEGQQDEQL DLDFVEAKYT IGDIFVHSPQ
150 151
RGLHPIRQRS NSDVTISDID AEDVLDQNAV NPNTGAALHR EYGSTSSIDR
200 201
QGLSGENFFA MLRGYRVENY DHKAMVPFGF PEFFRCDPAI SPSLHAAAQI
250 251
SRGEFVRISG LDYVDSALLM GRDRDKPFKR RLKSESVETS LFRKLRTVKS
300 301
EHETFKFTSE LEESRLERGI RPWNCQRCFA HYDVQSILFN INEAMATRAN
350 351
VGKRKNITTG ASAASQTQMP TGQTGNCESP LGSKEDLNSK ENLDADEGDG
400 401
KSNDLVLSCP YFRNETGGEG DRRIALSRAN SSSFSSGESC SFESSLSSHC
450 451
TNAGVSVLEV PRENQPIHRE KVKRYIIEHI DLGAYYYRKF FYGKEHQNYF
500 501
GIDENLGPVA VSIRREKVED AKEKEGSQFN YRVAFRTSEL TTLRGAILED
550 551
AIPSTARHGT ARGLPLKEVL EYVIPELSIQ CLRQASNSPK VSEQLLKLDE
600 601
QGLSFQHKIG ILYCKAGQST EEEMYNNETA GPAFEEFLDL LGQRVRLKGF
650 651
SKYRAQLDNK TDSTGTHSLY TTYKDYELMF HVSTLLPYMP NNRQQLLRKR
700 701
HIGNDIVTIV FQEPGALPFT PKSIRSHFQH VFVIVKVHNP CTENVCYSVG
750 751
VSRSKDVPPF GPPIPKGVTF PKSAVFRDFL LAKVINAENA AHKSEKFRAM
800 801
ATRTRQEYLK DLAENFVTTA TVDTSVKFSF ITLGAKKKEK VKPRKDAHLF
850 851
SIGAIMWHVI ARDFGQSADI ECLLGISNEF IMLIEKDSKN VVFNCSCRDV
900 901
IGWTSGLVSI KVFYERGECV LLSSVDNCAE DIREIVQRLV IVTRGCETVE
950 951
MTLRRNGLGQ LGFHVNFEGI VADVEPFGFA WKAGLRQGSR LVEICKVAVA
1000 1001
TLTHEQMIDL LRTSVTVKVV IIQPHDDGSP RRGCSELCRI PMVEYKLDSE
1050 1051
GTPCEYKTPF RRNTTWHRVP TPALQPLSRA SPIPGTPDRL PCQQLLQQAQ
1100 1101
AAIPRSTSFD RKLPDGTRSS PSNQSSSSDP GPGGSGPWRP QVGYDGCQSP
1150 1151
LLLEHQGSGP LECDGARERE DTMEASRHPE TKWHGPPSKV LGSYKERALQ
1200 1201
KDGSCKDSPN KLSHIGDKSC SSHSSSNTLS SNTSSNSDDK HFGSGDLMDP
1250 1251
ELLGLTYIKG ASTDSGIDTA PCMPATILGP VHLAGSRSLI HSRAEQWADA
1300 1301
ADVSGPDDEP AKLYSVHGYA STISAGSAAE GSMGDLSEIS SHSSGSHHSG
1350 1351
SPSAHCSKSS GSLDSSKVYI VSHSSGQQVP GSMSKPYHRQ GAVNKYVIGW
1400 1401
KKSEGSPPPE EPEVTECPGM YSEMDVMSTA TQHQTVVGDA VAETQHVLSK
1450 1451
EDFLKLMLPD SPLVEEGRRK FSFYGNLSPR RSLYRTLSDE SICSNRRGSS
1500 1501
FGSSRSSVLD QALPNDILFS TTPPYHSTLP PRAHPAPSMG SLRNEFWFSD
1550 1551
GSLSDKSKCA DPGLMPLPDT ATGLDWTHLV DAARAFEGLD SDEELGLLCH
1600 1601
HTSYLDQRVA SFCTLTDMQH GQDLEGAQEL PLCVDPGSGK EFMDTTGERS
1650 1651
PSPLTGKVNQ LELILRQLQT DLRKEKQDKA VLQAEVQHLR QDNMRLQEES
1700 1701
QTATAQLRKF TEWFFTTIDK KS
1722
Show the unformatted sequence. |
| Checksums: |
CRC64:C99E808CD6B156B1
MD5:4e53de251a74704999752663c3d7dee7
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
