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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: STX18_HUMAN (Q9P2W9)

Summary

This is the summary of UniProt entry STX18_HUMAN (Q9P2W9).

Description: Syntaxin-18
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 335 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Syntaxin-18_N 3 96
low_complexity n/a 24 33
disorder n/a 34 45
disorder n/a 50 51
disorder n/a 86 91
disorder n/a 96 99
disorder n/a 114 126
disorder n/a 164 231
coiled_coil n/a 232 252
disorder n/a 233 234
transmembrane n/a 312 333

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9P2W9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVDITLLFR ASVKTVKTRN KALGVAVGGG VDGSRDELFR RSPRPKGDFS
50
51
SRAREVISHI GKLRDFLLEH RKDYINAYSH TMSEYGRMTD TERDQIDQDA
100
101
QIFMRTCSEA IQQLRTEAHK EIHSQQVKEH RTAVLDFIED YLKRVCKLYS
150
151
EQRAIRVKRV VDKKRLSKLE PEPNTKTRES TSSEKVSQSP SKDSEENPAT
200
201
EERPEKILAE TQPELGTWGD GKGEDELSPE EIQMFEQENQ RLIGEMNSLF
250
251
DEVRQIEGRV VEISRLQEIF TEKVLQQEAE IDSIHQLVVG ATENIKEGNE
300
301
DIREAIKNNA GFRVWILFFL VMCSFSLLFL DWYDS                
335
 

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Checksums:
CRC64:D89B3B52407D77FF
MD5:f63144d5d353f4a6d92e3b5049bcbd01

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;