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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PARG_RAT (Q9QYM2)

Summary

This is the summary of UniProt entry PARG_RAT (Q9QYM2).

Description: Poly(ADP-ribose) glycohydrolase {ECO:0000303|PubMed:10502684}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 972 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 63
disorder n/a 66 220
disorder n/a 247 355
low_complexity n/a 286 298
low_complexity n/a 322 329
disorder n/a 361 455
disorder n/a 461 462
disorder n/a 465 466
disorder n/a 513 520
Pfam PARG_cat 577 905
low_complexity n/a 875 889
low_complexity n/a 925 933
disorder n/a 962 972

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9QYM2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSAGPGCEPC TKRPRWGAAG TSAPTASDSR SFPGRQKRVL DPKDAPVQFR
50
51
VPPSSSACVS GRAGPHRGSV TSFVFKQKPI TTWMDTKGPK TAESESKENN
100
101
NTRTDPMMSS VQKDNFYPHK VEKLGNVPQL NLDKSPTEKS TPYLNQQQTA
150
151
GVCKWHSAGE RAEQLSASEP SAVTQAPKQL SNANIDQSPP TDGHSDTDHE
200
201
EDRDNQQFLT PVKLANAKQT VGDGQARSNC KCSASCQCGQ DCAGCQREEA
250
251
DVIPESPLSD VGAEDIGTGS KNDNKLTGQE SGLGDSPPFE KESEPESPMD
300
301
VDNSKTSCQD SEADEEASPV FDEQDDQDDR SSQTANKLSS RQAREVDGDL
350
351
RKRYLTKGSE IRLHFQFEGG SNAGTSDLNA KPSGNSSSLN VDGRSSKQHG
400
401
KRDSKITDHF VRIPKSEDKR KEQCEVRHQR AERKIPKYVP PNLPPDKKWL
450
451
GTPIEEMRKM PRCGVRLPLL RPSASHTVTV RVDLLRAGEV PKPFPTHYKD
500
501
LWDNKHVKMP CSEQNLYPVE DENGERTAGS RWELIQTALL NKFTRPQNLK
550
551
DAILKYNVAY SKKWDFTALV DFWDKVLEEA EAQHLYQSIL PDMVKIALCL
600
601
PNICTQPIPL LKQKMNHSVT MSQEQIASLL ANAFFCTFPR RNAKMKSEYS
650
651
SYPDINFNRL FEGRSSRKPE KLKTLFCYFR RVTEKKPTGL VTFTRQSLED
700
701
FPEWERCDKP LTRLHVTYEG TIEGNGRGML QVDFANRFVG GGVTGAGLVQ
750
751
EEIRFLINPE LIVSRLFTEV LDHNECLIIT GTEQYSEYTG YAETYRWARS
800
801
HEDGSEKDDW QRCCTEIVAI DALHFRRYLD QFVPEKVRRE LNKAYCGFLR
850
851
PGVPPENLSA VATGNWGCGA FGGDARLKAL IQLLAAAAAE RDVVYFTFGD
900
901
SELMRDIYSM HTFLTERKLN VGKVYRLLLR YYREECRDCS SPGPDTKLYP
950
951
FIYHAAESSA ETSDQPGQRT GT                              
972
 

Show the unformatted sequence.

Checksums:
CRC64:3DED7885684F59E9
MD5:5d90c02726fb6ff7dedf8de4ed2fa5b8

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PARG_cat 577 - 905 3UEK A 577 - 905 Show 3D Structure View in InterPro
3UEL A 577 - 905 Show 3D Structure View in InterPro
B 577 - 905 Show 3D Structure View in InterPro
C 577 - 905 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;