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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: BIR1E_MOUSE (Q9R016)

Summary

This is the summary of UniProt entry BIR1E_MOUSE (Q9R016).

Description: Baculoviral IAP repeat-containing protein 1e
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1403 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 5
low_complexity n/a 36 51
disorder n/a 40 41
disorder n/a 43 52
Pfam BIR 63 128
Pfam BIR 162 228
Pfam BIR 281 346
disorder n/a 365 379
Pfam NACHT 464 618
Pfam NOD2_WH 688 743
Pfam NLRC4_HD 767 873
low_complexity n/a 851 862

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9R016. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEHGESSED RISEIDYEFL PELSALLGVD AFQVAKSQEE EEHKERMKMK
50
51
KGFNSQMRSE AKRLKTFETY DTFRSWTPQE MAAAGFYHTG VRLGVQCFCC
100
101
SLILFGNSLR KLPIERHKKL RPECEFLQGK DVGNIGKYDI RVKRPEKMLR
150
151
GGKARYHEEE ARLESFEDWP FYAHGTSPRV LSAAGFVFTG KRDTVQCFSC
200
201
GGSLGNWEEG DDPWKEHAKW FPKCEFLQSK KSSEEIAQYI QSYEGFVHVT
250
251
GEHFVKSWVR RELPMVSAYC NDSVFANEEL RMDMFKDWPQ ESPVGVEALV
300
301
RAGFFYTGKK DIVRCFSCGG CLEKWAEGDD PMEDHIKFFP ECVFLQTLKS
350
351
SAEVIPTLQS QYALPEATET TRESNHGDAA AVHSTVVDLG RSEAQWFQEA
400
401
RSLSEQLRDN YTKATFRHMN LPEVCSSLGT DHLLSCDVSI ISKHISQPVQ
450
451
EALTIPEVFS NLNSVMCVEG ETGSGKTTFL KRIAFLWASG CCPLLYRFQL
500
501
VFYLSLSSIT PDQGLANIIC AQLLGAGGCI SEVCLSSSIQ QLQHQVLFLL
550
551
DDYSGLASLP QALHTLITKN YLSRTCLLIA VHTNRVRDIR LYLGTSLEIQ
600
601
EFPFYNTVSV LRKFFSHDII CVEKLIIYFI DNKDLQGVYK TPLFVAAVCT
650
651
DWIQNASAQD KFQDVTLFQS YMQYLSLKYK ATAEPLQATV SSCGQLALTG
700
701
LFSSCFEFNS DDLAEAGVDE DEKLTTLLMS KFTAQRLRPV YRFLGPLFQE
750
751
FLAAVRLTEL LSSDRQEDQD LGLYYLRQID SPLKAINSFN IFLYYVSSHS
800
801
SSKAAPTVVS HLLQLVDEKE SLENMSENED YMKLHPQTFL WFQFVRGLWL
850
851
VSPESSSSFV SEHLLRLALI FAYESNTVAE CSPFILQFLR GKTLALRVLN
900
901
LQYFRDHPES LLLLRSLKVS INGNKMSSYV DYSFKTYFEN LQPPAIDEEY
950
951
TSAFEHISEW RRNFAQDEEI IKNYENIRPR ALPDISEGYW KLSPKPCKIP
1000
1001
KLEVQVNNTD AADQALLQVL MEVFSASQSI EFRLFNSSGF LESICPALEL
1050
1051
SKASVTKCSM SRLELSRAEQ ELLLTLPALQ SLEVSETNQL PEQLFHNLHK
1100
1101
FLGLKELCVR LDGKPNVLSV LPREFPNLLH MEKLSIQTST ESDLSKLVKF
1150
1151
IQNFPNLHVF HLKCDFLSNC ESLMAVLASC KKLREIEFSG RCFEAMTFVN
1200
1201
ILPNFVSLKI LNLKDQQFPD KETSEKFAQA LGSLRNLEEL LVPTGDGIHQ
1250
1251
VAKLIVRQCL QLPCLRVLTF HDILDDDSVI EIARAATSGG FQKLENLDIS
1300
1301
MNHKITEEGY RNFFQALDNL PNLQELNICR NIPGRIQVQA TTVKALGQCV
1350
1351
SRLPSLIRLH MLSWLLDEED MKVINDVKER HPQSKRLIIF WKLIVPFSPV
1400
1401
ILE                                                   
1403
 

Show the unformatted sequence.

Checksums:
CRC64:04C04877908103EE
MD5:214e321195fae61f767bfe9f6ea2632a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
BIR 162 - 228 5YUD A 162 - 228 Show 3D Structure View in InterPro
6B5B A 162 - 228 Show 3D Structure View in InterPro
281 - 346 6B5B A 281 - 346 Show 3D Structure View in InterPro
63 - 121 6B5B A 63 - 121 Show 3D Structure View in InterPro
63 - 128 5YUD A 63 - 128 Show 3D Structure View in InterPro
NACHT 464 - 618 5YUD A 464 - 618 Show 3D Structure View in InterPro
6B5B A 464 - 618 Show 3D Structure View in InterPro
NLRC4_HD 767 - 873 5YUD A 767 - 873 Show 3D Structure View in InterPro
6B5B A 767 - 873 Show 3D Structure View in InterPro
NOD2_WH 688 - 743 5YUD A 688 - 743 Show 3D Structure View in InterPro
6B5B A 688 - 743 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;