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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: IRE1L_ARATH (Q9SF12)

Summary

This is the summary of UniProt entry IRE1L_ARATH (Q9SF12).

Description: Inactive serine/threonine-protein kinase/endoribonuclease IRE1-like
Source organism: Arabidopsis thaliana (Mouse-ear cress) (NCBI taxonomy ID 3702)
Length: 554 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 23
low_complexity n/a 3 20
disorder n/a 31 84
disorder n/a 114 117
Pfam Pkinase 127 408
low_complexity n/a 241 252
low_complexity n/a 294 308
disorder n/a 320 327
disorder n/a 358 364
disorder n/a 366 368
Pfam Ribonuc_2-5A 414 553
low_complexity n/a 485 501

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9SF12. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MWLLAISLVG LLVVVVCVFL RFSKDKGLDG IVNEKKRDKN SAPRVSASGE
50
51
DGTKNEQVEK KSDPSGGLGE ENEKTNSESK VLSVPSDQNI NKTLPVMLPS
100
101
LELRKYDENE TPGKVVNRRL LVSTNEMKYG RNGYEVFQGV YGRRSSVAVK
150
151
CLDLAHTTEA FIQNEIDNHC LCDDHSNIIR FHGLEQDQSF AYICLEPWKC
200
201
SLDDLIKLSV RRTKRDTQAV APVDDLEKVM KRIKFWKEKG KPLPLTPMLK
250
251
LMRDVVCGLA HLHKLKTIHR NLNPQNVLII VKDMTLTAKI SDMSLSKHLG
300
301
GKKSSYKHLA TCSGSSGWQA PEQLNKDKKK KEDFPADMFN FGCLLHYAVM
350
351
GTHPFGSPSE RDTNIKTNNK TNLSLVTNLE AINLIEQLLN YKPDLRPSAT
400
401
QVLLHPLFWD SEKRLFFLRE ASDRIELDIT MWGDLNKTIA PRVLGESKDW
450
451
ASKLGKTFIT HIENLAQAQP GQESRQYNRS YKYWSLRHLL RLIRNILSHH
500
501
REILDDPKIK EMVGKVPEGL DIFFTARFPN LMMEIYAFIS MHCKGEEAFE
550
551
KYFN                                                  
554
 

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Checksums:
CRC64:3543FFF1A6651683
MD5:8b3ffac54a39a2db6510b7fe10c59e78

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;