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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: P53_PIG (Q9TUB2)

Summary

This is the summary of UniProt entry P53_PIG (Q9TUB2).

Description: Cellular tumor antigen p53
Source organism: Sus scrofa (Pig) (NCBI taxonomy ID 9823)
Length: 386 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 13
Pfam P53_TAD 6 30
low_complexity n/a 25 38
disorder n/a 55 76
low_complexity n/a 64 81
Pfam P53 91 282
disorder n/a 175 176
disorder n/a 279 319
Pfam P53_tetramer 312 351
disorder n/a 336 386

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9TUB2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEESQSELGV EPPLSQETFS DLWKLLPENN LLSSELSLAA VNDLLLSPVT
50
51
NWLDENPDDA SRVPAPPAAT APAPAAPAPA TSWPLSSFVP SQKTYPGSYD
100
101
FRLGFLHSGT AKSVTCTYSP ALNKLFCQLA KTCPVQLWVS SPPPPGTRVR
150
151
AMAIYKKSEY MTEVVRRCPH HERSSDYSDG LAPPQHLIRV EGNLRAEYLD
200
201
DRNTFRHSVV VPYEPPEVGS DCTTIHYNFM CNSSCMGGMN RRPILTIITL
250
251
EDASGNLLGR NSFEVRVCAC PGRDRRTEEE NFLKKGQSCP EPPPGSTKRA
300
301
LPTSTSSSPV QKKKPLDGEY FTLQIRGRER FEMFRELNDA LELKDAQTAR
350
351
ESGENRAHSS HLKSKKGQSP SRHKKPMFKR EGPDSD               
386
 

Show the unformatted sequence.

Checksums:
CRC64:A4C3D88E8DF55162
MD5:18e6cdcaefe856d950895c2928319515

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;