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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CLIP2_HUMAN (Q9UDT6)

Summary

This is the summary of UniProt entry CLIP2_HUMAN (Q9UDT6).

Description: CAP-Gly domain-containing linker protein 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1046 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 74
low_complexity n/a 26 37
low_complexity n/a 47 69
Pfam CAP_GLY 81 145
disorder n/a 108 112
disorder n/a 114 117
disorder n/a 141 173
disorder n/a 182 184
disorder n/a 196 214
Pfam CAP_GLY 221 285
disorder n/a 296 299
disorder n/a 301 311
low_complexity n/a 313 337
disorder n/a 322 327
disorder n/a 334 335
disorder n/a 337 339
disorder n/a 341 344
coiled_coil n/a 354 381
disorder n/a 358 359
coiled_coil n/a 396 455
disorder n/a 456 466
coiled_coil n/a 470 494
disorder n/a 522 546
low_complexity n/a 542 549
disorder n/a 554 559
disorder n/a 561 562
coiled_coil n/a 564 612
disorder n/a 592 601
disorder n/a 603 616
disorder n/a 618 650
disorder n/a 663 665
disorder n/a 667 688
coiled_coil n/a 675 702
disorder n/a 690 691
coiled_coil n/a 704 800
disorder n/a 714 730
disorder n/a 770 771
disorder n/a 801 802
disorder n/a 805 823
disorder n/a 825 837
disorder n/a 839 841
disorder n/a 843 844
disorder n/a 853 855
coiled_coil n/a 853 887
low_complexity n/a 868 881
disorder n/a 881 884
disorder n/a 915 918
disorder n/a 920 935
coiled_coil n/a 936 963
disorder n/a 952 954
disorder n/a 957 962
disorder n/a 968 972
coiled_coil n/a 983 1010
disorder n/a 984 989
disorder n/a 994 1005
disorder n/a 1007 1046

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UDT6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG
50
51
PSSSPAAAAA PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE
100
101
TQFAPGQWAG VVLDDPVGKN DGAVGGVRYF ECPALQGIFT RPSKLTRQPT
150
151
AEGSGSDAHS VESLTAQNLS LHSGTATPPL TSRVIPLRES VLNSSVKTGN
200
201
ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE TDFAKGEWCG
250
251
VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK
300
301
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK
350
351
ISGTTALQEA LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK
400
401
AQHEQYVAEA EEKLQRARLL VESVRKEKVD LSNQLEEERR KVEDLQFRVE
450
451
EESITKGDLE TQTQLEHARI GELEQSLLLE KAQAERLLRE LADNRLTTVA
500
501
EKSRVLQLEE ELTLRRGEIE ELQQCLLHSG PPPPDHPDAA EILRLRERLL
550
551
SASKEHQRES GVLRDKYEKA LKAYQAEVDK LRAANEKYAQ EVAGLKDKVQ
600
601
QATSENMGLM DNWKSKLDSL ASDHQKSLED LKATLNSGPG AQQKEIGELK
650
651
AVMEGIKMEH QLELGNLQAK HDLETAMHVK EKEALREKLQ EAQEELAGLQ
700
701
RHWRAQLEVQ ASQHRLELQE AQDQRRDAEL RVHELEKLDV EYRGQAQAIE
750
751
FLKEQISLAE KKMLDYERLQ RAEAQGKQEV ESLREKLLVA ENRLQAVEAL
800
801
CSSQHTHMIE SNDISEETIR TKETVEGLQD KLNKRDKEVT ALTSQTEMLR
850
851
AQVSALESKC KSGEKKVDAL LKEKRRLEAE LETVSRKTHD ASGQLVLISQ
900
901
ELLRKERSLN ELRVLLLEAN RHSPGPERDL SREVHKAEWR IKEQKLKDDI
950
951
RGLREKLTGL DKEKSLSDQR RYSLIDRSSA PELLRLQHQL MSTEDALRDA
1000
1001
LDQAQQVEKL MEAMRSCPDK AQTIGNSGSA NGIHQQDKAQ KQEDKH    
1046
 

Show the unformatted sequence.

Checksums:
CRC64:7A0B3C796E1C6E25
MD5:304fc853d8cfd650bdba72cdb0017f2b

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CAP_GLY 221 - 285 2CP3 A 10 - 74 Jmol OpenAstexViewer
81 - 145 2CP2 A 21 - 85 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.